Structure of PDB 1trz Chain D Binding Site BS01

Receptor Information
>1trz Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1trz Chain C (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1trz Crystallographic evidence for dual coordination around zinc in the T3R3 human insulin hexamer.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		Q4 C7 L11 L15 C19 R22 G23 F24 F25
Binding residue
(residue number reindexed from 1)		Q4 C7 L11 L15 C19 R22 G23 F24 F25
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1trz, PDBe:1trz, PDBj:1trz
PDBsum1trz
PubMed8312271
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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