Structure of PDB 1scf Chain D Binding Site BS01

Receptor Information
>1scf Chain D (length=104) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVVQLSDSLTDLL
DKFSNISEGLSNYSIIDKLVNIVDDLVECVSPEPRLFTPEEFFRIFNRSI
DAFK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1scf Chain D Residue 1022 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1scf Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
D54 D58
Binding residue
(residue number reindexed from 1)
D44 D48
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005173 stem cell factor receptor binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1scf, PDBe:1scf, PDBj:1scf
PDBsum1scf
PubMed10880433
UniProtP21583|SCF_HUMAN Kit ligand (Gene Name=KITLG)

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