Structure of PDB 1s7v Chain D Binding Site BS01

Receptor Information
>1s7v Chain D (length=276) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVT
LRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVP
LGKEQNYTCRVYHEGLPEPLTLRWEP
Ligand information
>1s7v Chain F (length=9) Species: 11627 (Lymphocytic choriomeningitis virus (strain WE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KAVYNLATM
Receptor-Ligand Complex Structure
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PDB1s7v Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Y7 Y59 R62 E63 K66 Q70 W73 S77 N80 Y84 Q97 F116 Y123 T143 K146 W147 H155 Y156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 Y59 R62 E63 K66 Q70 W73 S77 N80 Y84 Q97 F116 Y123 T143 K146 W147 H155 Y156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0001913 T cell mediated cytotoxicity
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0006955 immune response
GO:0010977 negative regulation of neuron projection development
GO:0019882 antigen processing and presentation
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0098553 lumenal side of endoplasmic reticulum membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1s7v, PDBe:1s7v, PDBj:1s7v
PDBsum1s7v
PubMed15100292
UniProtP01899|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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