Structure of PDB 1r5w Chain D Binding Site BS01
Receptor Information
>1r5w Chain D (length=185) Species:
10090
(Mus musculus) [
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APWFLEYSKSECHFYNGTQRVRLLVRYFYNLEENLRFDSDVGEFRAVTEL
GRPDAENWNSQPEFLEQKRAEVDTVCRHNYEIFDNFLVPRRVEPTVTVYP
TKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDW
TFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEW
Ligand information
>1r5w Chain F (length=13) [
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ADLIAYFKAATKF
Receptor-Ligand Complex Structure
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PDB
1r5w
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
E36 S40 N87 W88 V105 N109 I112
Binding residue
(residue number reindexed from 1)
E6 S10 N57 W58 V75 N79 I82
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:1r5w
,
PDBe:1r5w
,
PDBj:1r5w
PDBsum
1r5w
PubMed
14690592
UniProt
Q31164
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