Structure of PDB 1qzh Chain D Binding Site BS01

Receptor Information

>1qzh Chain D (length=170) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VIDSLQLNELLNAGEYKIGELTFQSIRSSQELQKKNTIVNLFGIVKDFTP
SRQSLHGTKDWVTTVYLWDPTCDTSSIGLQIHLFSKQGNDLPVIKQVGQP
LLLHQITLRSYRDRTQGLSKDQFRYALWPDFSSNSKDTLCPQPMPRLMKT
GDKEEQFALLLNKIWDEQTN

Ligand information

>1qzh Chain J (length=6) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggttac

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1qzh DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Resolution	2.4 Å
Binding residue (original residue number in PDB)	R56 S58 L59 G61 T62 D64 H86 F88 T111 R113 Y115 Q120 L122 S123 K124 D125
Binding residue (residue number reindexed from 1)	R52 S54 L55 G57 T58 D60 H82 F84 T107 R109 Y111 Q116 L118 S119 K120 D121

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0043047	single-stranded telomeric DNA binding

	Biological Process
GO:0000723	telomere maintenance

	Cellular Component
GO:0000781	chromosome, telomeric region

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Cellular Component

External links

PDB	RCSB:1qzh, PDBe:1qzh, PDBj:1qzh
PDBsum	1qzh
PubMed	14614509
UniProt	O13988\|POT1_SCHPO Protection of telomeres protein 1 (Gene Name=pot1)

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