Structure of PDB 1qvo Chain D Binding Site BS01

Receptor Information
>1qvo Chain D (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>1qvo Chain F (length=10) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QVPLRPMTYK
Receptor-Ligand Complex Structure
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PDB1qvo Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
Resolution2.22 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 A69 Q70 T73 V76 D77 Y84 Y99 R114 D116 W133 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 A69 Q70 T73 V76 D77 Y84 Y99 R114 D116 W133 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1qvo, PDBe:1qvo, PDBj:1qvo
PDBsum1qvo
PubMed15128805
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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