Structure of PDB 1pk8 Chain D Binding Site BS01

Receptor Information
>1pk8 Chain D (length=300) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGF
SVDMEVVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLH
SVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVV
VKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQ
KIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGL
DICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1pk8 Chain D Residue 817 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1pk8 Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		E373 E386
Binding residue
(residue number reindexed from 1)		E256 E269
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007269 neurotransmitter secretion
Cellular Component
GO:0008021 synaptic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1pk8, PDBe:1pk8, PDBj:1pk8
PDBsum1pk8
PubMed14688264
UniProtP09951|SYN1_RAT Synapsin-1 (Gene Name=Syn1)

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