Structure of PDB 1ol2 Chain D Binding Site BS01

Receptor Information
>1ol2 Chain D (length=258) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
Ligand information
Receptor-Ligand Complex Structure
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PDB1ol2 Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange
Resolution2.6 Å
Binding residue
(original residue number in PDB)
M210 E220 R250 Q254 T282
Binding residue
(residue number reindexed from 1)
M36 E46 R76 Q80 T108
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function

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Biological Process
External links
PDB RCSB:1ol2, PDBe:1ol2, PDBj:1ol2
PDBsum1ol2
PubMed14656438
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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