Structure of PDB 1ol2 Chain D Binding Site BS01
Receptor Information
>1ol2 Chain D (length=258) Species:
9606
(Homo sapiens) [
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VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
Ligand information
>1ol2 Chain F (length=5) Species:
32630
(synthetic construct) [
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RRLNF
Receptor-Ligand Complex Structure
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PDB
1ol2
Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
M210 E220 R250 Q254 T282
Binding residue
(residue number reindexed from 1)
M36 E46 R76 Q80 T108
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0016538
cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772
mitotic cell cycle phase transition
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Molecular Function
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Biological Process
External links
PDB
RCSB:1ol2
,
PDBe:1ol2
,
PDBj:1ol2
PDBsum
1ol2
PubMed
14656438
UniProt
P20248
|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)
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