Structure of PDB 1ol1 Chain D Binding Site BS01

Receptor Information

>1ol1 Chain D (length=258) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL

Ligand information

>1ol1 Chain H (length=5) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

RRLIF

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1ol1 Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange
Resolution	2.9 Å
Binding residue (original residue number in PDB)	M210 W217 Q254 I281 T282 D283
Binding residue (residue number reindexed from 1)	M36 W43 Q80 I107 T108 D109

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity

	Biological Process
GO:0044772	mitotic cell cycle phase transition

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Molecular Function

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Biological Process

External links

PDB	RCSB:1ol1, PDBe:1ol1, PDBj:1ol1
PDBsum	1ol1
PubMed	14656438
UniProt	P20248\|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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