Structure of PDB 1odj Chain D Binding Site BS01

Receptor Information
>1odj Chain D (length=234) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPIHVRAHPGDVAERVLLPGDPGRAEWIAKTFLQNPRRYNDHRGLWGYTG
LYKGVPVSVQTTGMGTPSAAIVVEELVRLGARVLVRVGTAGAASSDLAPG
ELIVAQGAVPLDGTTRQYLEGRPYAPVPDPEVFRALWRRAEALGYPHRVG
LVASEDAFYATTPEEARAWARYGVLAFEMEASALFLLGRMRGVRTGAILA
VSNRIGDPELAPPEVLQEGVRRMVEVALEAVLEV
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1odj Chain D Residue 1236 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1odj Crystal Structure of Purine Nucleoside Phosphorylase from Thermus Thermophilus
Resolution2.4 Å
Binding residue
(original residue number in PDB)
G21 R25 R87 T90
Binding residue
(residue number reindexed from 1)
G20 R24 R86 T89
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H5 G21 R25 R44 E76 R87 T90 S203 N204 I206 L217
Catalytic site (residue number reindexed from 1) H4 G20 R24 R43 E75 R86 T89 S202 N203 I205 L216
Enzyme Commision number 2.4.2.3: uridine phosphorylase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1odj, PDBe:1odj, PDBj:1odj
PDBsum1odj
PubMed15046984
UniProtQ5SID9

[Back to BioLiP]