Structure of PDB 1m2z Chain D Binding Site BS01

Receptor Information
>1m2z Chain D (length=253) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAA
VKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFA
PDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS
VPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDS
MHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLF
HQK
Ligand information
>1m2z Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PVSPKKKENALLRYLLDKDDT
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1m2z Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K579 R585 M593 Q597 E755 T758 N759
Binding residue
(residue number reindexed from 1)		K55 R61 M69 Q73 E231 T234 N235
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1m2z, PDBe:1m2z, PDBj:1m2z
PDBsum1m2z
PubMed12151000
UniProtP04150|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)

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