Structure of PDB 1m0d Chain D Binding Site BS01

Receptor Information

>1m0d Chain D (length=129) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SGLEDKVSKQLESKGIKFEYEEWKVPYVIPASNHTYTPDFLLPNGIFVET
KGLWESDDRKKHLLIREQHPELDIRIVFSSSRTKLYKGSPTSYGEFCEKH
GIKFADKLIPAEWIKEPKKEVPFDRLKRK

Ligand information

InChI=1S/Mn/q+2

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Mn

Name

MANGANESE (II) ION

PDB chain

1m0d Chain D Residue 7 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	1m0d Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I.
Resolution	1.9 Å
Binding residue (original residue number in PDB)	D55 E65 T66
Binding residue (residue number reindexed from 1)	D39 E49 T50
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.21.2: deoxyribonuclease IV.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0008821	crossover junction DNA endonuclease activity
GO:0008833	deoxyribonuclease IV (phage-T4-induced) activity
GO:1990238	double-stranded DNA endonuclease activity

	Biological Process
GO:0015074	DNA integration
GO:0016032	viral process
GO:0039657	symbiont-mediated suppression of host gene expression
GO:0099015	degradation of host chromosome by virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:1m0d, PDBe:1m0d, PDBj:1m0d
PDBsum	1m0d
PubMed	12093751
UniProt	P00641\|ENDO_BPT7 Endonuclease I (Gene Name=3)

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