Structure of PDB 1h28 Chain D Binding Site BS01

Receptor Information
>1h28 Chain D (length=258) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1h28 Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Resolution2.8 Å
Binding residue
(original residue number in PDB)		M210 W217 E220 R250 G251 Q254 Y280 I281 T285
Binding residue
(residue number reindexed from 1)		M36 W43 E46 R76 G77 Q80 Y106 I107 T111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:1h28, PDBe:1h28, PDBj:1h28
PDBsum1h28
PubMed12501191
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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