Structure of PDB 1gxc Chain D Binding Site BS01
Receptor Information
>1gxc Chain D (length=116) Species:
9606
(Homo sapiens) [
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PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSK
KHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIAL
SLSRNKVFVFFDLTVD
Ligand information
>1gxc Chain B (length=8) Species:
32630
(synthetic construct) [
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HFDTYLIR
Receptor-Ligand Complex Structure
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PDB
1gxc
Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
N186 E188 V200 F202 V206 D207
Binding residue
(residue number reindexed from 1)
N95 E97 V109 F111 V115 D116
Enzymatic activity
Enzyme Commision number
2.7.11.1
: non-specific serine/threonine protein kinase.
External links
PDB
RCSB:1gxc
,
PDBe:1gxc
,
PDBj:1gxc
PDBsum
1gxc
PubMed
12049740
UniProt
O96017
|CHK2_HUMAN Serine/threonine-protein kinase Chk2 (Gene Name=CHEK2)
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