Structure of PDB 1fyr Chain D Binding Site BS01

Receptor Information
>1fyr Chain D (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQH
FKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fyr Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R67 R86 S88 E89 S90 S96 Q106 H107 F108 K109 L120
Binding residue
(residue number reindexed from 1)		R10 R29 S31 E32 S33 S39 Q49 H50 F51 K52 L63
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1fyr, PDBe:1fyr, PDBj:1fyr
PDBsum1fyr
PubMed11063574
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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