Structure of PDB 1fsj Chain D Binding Site BS01

Receptor Information
>1fsj Chain D (length=132) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKSFDD
FRKAVWEEVSKDPELSKNLNPSNKSSVSKGYSPFTPKNQQVGGRKVYELH
HDKPISQGGEVYDMDNIRVTTPKRHIDIHRGK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1fsj Chain D Residue 903 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1fsj Specificity in protein-protein interactions: The structural basis for dual recognition in endonuclease colicin-immunity protein complexes
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H502 H527 H531
Binding residue
(residue number reindexed from 1)		H100 H125 H129
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) R405 R496 E500 H502 H503 H527 H531
Catalytic site (residue number reindexed from 1) R3 R94 E98 H100 H101 H125 H129
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005102 signaling receptor binding
Biological Process
GO:0009617 response to bacterium
GO:0019835 cytolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1fsj, PDBe:1fsj, PDBj:1fsj
PDBsum1fsj
PubMed
UniProtP09883|CEA9_ECOLX Colicin-E9 (Gene Name=col)

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