Structure of PDB 1fat Chain D Binding Site BS01

Receptor Information
>1fat Chain D (length=231) Species: 3885 (Phaseolus vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNDIYFNFQRFNETNLILQRDASVSSSGQLRLTNLNGEPRVGSLGRAFYS
APIQIWDNTTGTVASFATSFTFNIQVPNNAGPADGLAFALVPVGSQPKDK
GGFLGLFDGSNSNFHTVAVEFDTLYNKDWDPTERHIGIDVNSIRSIKTTR
WDFVNGENAEVLITYDSSTNLLVASLVYPSQKTSFIVSDTVDLKSVLPEW
VSVGFSATTGINKGNVETNDVLSWSFASKLS
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1fat Chain D Residue 254 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fat The crystallographic structure of phytohemagglutinin-L.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		E122 D124 D132 H137
Binding residue
(residue number reindexed from 1)		E120 D122 D130 H135
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005537 D-mannose binding
GO:0030246 carbohydrate binding
GO:0090729 toxin activity
Biological Process
GO:0006952 defense response
GO:0035821 modulation of process of another organism

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1fat, PDBe:1fat, PDBj:1fat
PDBsum1fat
PubMed8702788
UniProtP05087|PHAL_PHAVU Leucoagglutinating phytohemagglutinin (Gene Name=DLEC2)

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