Structure of PDB 1e8o Chain D Binding Site BS01

Receptor Information
>1e8o Chain D (length=76) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGNKCLLRATDGKKKIST
VVSSKEVNKFQMAYSNLLRANMDGLK
Ligand information
>1e8o Chain E (length=50) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggccgggcgcgguggcgcgcgccuguagucccagcuacucgggaggcuc
<<<<<<<<<<<<..(((.>>>>>>>....<<<<.)))....>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB1e8o Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle
Resolution3.2 Å
Binding residue
(original residue number in PDB)		V2 G24 Y27 K31 R59 K64 K66
Binding residue
(residue number reindexed from 1)		V1 G23 Y26 K30 R40 K45 K47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008312 7S RNA binding
GO:0030942 endoplasmic reticulum signal peptide binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005786 signal recognition particle, endoplasmic reticulum targeting
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1e8o, PDBe:1e8o, PDBj:1e8o
PDBsum1e8o
PubMed11089964
UniProtP37108|SRP14_HUMAN Signal recognition particle 14 kDa protein (Gene Name=SRP14)

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