Structure of PDB 1dm5 Chain D Binding Site BS01

Receptor Information
>1dm5 Chain D (length=315) Species: 6087 (Hydra vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQI
KTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGL
GTDKNALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLL
VSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSY
PQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAE
RLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADD
CSGDYKDLLLQITGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1dm5 Chain D Residue 1124 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dm5 Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization.
Resolution1.93 Å
Binding residue
(original residue number in PDB)		M98 K99 G100 G102 E142
Binding residue
(residue number reindexed from 1)		M97 K98 G99 G101 E141
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1dm5, PDBe:1dm5, PDBj:1dm5
PDBsum1dm5
PubMed10704197
UniProtP26256|ANX12_HYDVU Annexin-B12 (Gene Name=ANXB12)

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