Structure of PDB 1dlh Chain D Binding Site BS01

Receptor Information
>1dlh Chain D (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFDA
Ligand information
>1dlh Chain F (length=13) Species: 387147 (Influenza A virus (A/England/878/1969(H3N2))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PKYVKQNTLKLAT
Receptor-Ligand Complex Structure
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PDB1dlh Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Q9 F32 W43 A52 S53 F54 G58 N62 V65 N69 I72
Binding residue
(residue number reindexed from 1)		Q7 F30 W41 A50 S51 F52 G56 N60 V63 N67 I70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1dlh, PDBe:1dlh, PDBj:1dlh
PDBsum1dlh
PubMed8145819
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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