Structure of PDB 1c0w Chain D Binding Site BS01

Receptor Information
>1c0w Chain D (length=175) Species: 1717 (Corynebacterium diphtheriae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDLVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERD
GLVVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEA
CRWEHVMSDEVERRLVKVLKDVSRSPFGNPIPGLDELGVVQINEIFQVET
DQFTQLLDADIRVVELLDDLAHTIR
Ligand information
Receptor-Ligand Complex Structure
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PDB1c0w Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R27 A28 S42
Binding residue
(residue number reindexed from 1)		R26 A27 S41
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0017124 SH3 domain binding
GO:0042802 identical protein binding
GO:0046914 transition metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1c0w, PDBe:1c0w, PDBj:1c0w
PDBsum1c0w
PubMed10497029
UniProtP0DJL7|DTXR_CORDI Diphtheria toxin repressor (Gene Name=dtxR)

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