Structure of PDB 8pv5 Chain Cz Binding Site BS01

Receptor Information
>8pv5 Chain Cz (length=101) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNLGMRKNGQVWLPAKKAFRPTKGLTSWELRVKKRQEQAAMKAKEREMKE
EKEAERQKRIQAIKERRKKKEEKERYEQLAAKMHKKRLERLKRKEKRNKL
L
Ligand information
>8pv5 Chain C1 (length=3060) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacuau
gcuuggauagggugaagccagaggaaacucugguggaggcucgcagcggu
ucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacuaa
ucgaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcag
ugucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaa
gaagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacua
gugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgc
gggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguua
guacaucuugacagcaggacgguggccauggaagucggaauccgcuaagg
acuguguaacaacucaccugccgaauguacuagcccugaaaauggauggc
gcucaagcgucccacccauaccccgcccucaggguagaaacgaugcccug
aggaguaggcggccguggaggucagugacgaagccuagggcgugagcccg
ggucgaacggccucuagugcagaucuuggugguaguagcaaauacuucaa
ugagaacuugaaggaccgaaguggggaaagguuccaugugaacagcgguu
ggacauggguuagucgauccuaagccauagggaaguuccguuucaaaggg
gcacucgugccccguguggcgaaagggaagccgguuaauauuccggcacc
uggauguggguuuugcgcggcaacgcaacugaacgcggagacgacggcgg
gggccccgggcagaguucucuuuucuucuuaacggucuaucacccuggaa
acaguuugucuggagauaggguuuaauggccggaagagcccgacacuucu
gucggguccggugcgcucucgacgucccuugaaaauccgcgggagggaau
aauucucacgccaggucguacucauaaccgcagcagguccccaaggugaa
cagccucugguugauagaacaauguagauaagggaagucggcaaaauaga
uccguaacuucgggaaaaggauuggcucuaaggguugguaacaaccaacu
uagaacugguacggacagggggaaucugacugucuaauuaaaacauagca
uugcgauggccagaaagugguguugacgcaaugugauuucugcccagugc
ucugaaugucaaagugaagaaauucaaccaagcgcggguaaacggcggga
guaacuaugacucucuguagccaaauggauuaacgagauucccacugucc
cuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaau
cagcggggaaagaagacccuguugagcuugacucuaguuugacauuguga
aaagauuuuuuuacuuauucaaugaagcggggcuggacuugcguccaacu
ucuggaguuaagguccuucgcgggccgacccggguugaagacauugucag
guggggaguuuggcuggggcggcacaucugugcagguguccuaagggggg
cucauggagaacagaaaucuccaguagaacaaaaggguaaaaguccccuu
gauuuugauuuucagugugaauacaaaccaugaaaguguggccuaucgau
ccuuuagucccucgaaauuugaggcuagaggugccagaaaaguuaccaca
gggauggcuuguggcggccaagcguucauagcgacgucgcuuugauccuu
cgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguugga
uuguucacccacuaauagggaacgugagcuggguuuagaccgucgugaga
cagguuaguuuuacccuacugaugaacucgucgcaaugguaauucagcuu
aguacgagaggaaccgcugauucagauaauugguuuuugcgguuguccga
ccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccuc
uaagucagaauccaugccagaacgcgacgauacuacccgcacguuguaga
cguauaagaauaggcuccggccucguauccuagcaggcgauuccuccgcc
ggccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgc
gggaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaag
caguagaguagccuuguuguuacgaucugcugaggguaagcccuccuucg
ccuagauuuc
........................<<<<<<.....<......>......>
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>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<<...<<<<......>>>>.((..
....<<<.....))>>>.>..>>..>>.>>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<..(((((
(>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<...<<....>>..
.>>>>.>>.>>....>>>>.>>>>>>>>>.<<.<...<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.
<<.<<........>>>>>>>>....>>>>>>>>>...<<.......>>..
....>>>>>>......>.>>...<<<<<......<<<....>>>..<<<<
<<<<<.....<<.<<<<<<<.....<<<........>>.>.....>>>>>
...<<<<.<<<<.<......>>>>>.>>>>.....>>>>...>>>>>>>.
>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<
<<<<<...<<<(((.....<<<<<<.....<<..........<<<.<<<<
<<<<<<.......<<<<<.<<<...<<.........>>...>>>......
...<<......>>...>>>>>...>>>>>>>>>>>>>..........)))
.>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>
>>>....>>>>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>........>>>>>><<.....<<.....<<<<<<
.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.....>
>.>>>>>>....((<<<<<<...<<<...<<<....>>>........<<<
<<<....>>>>>>....>>>....>>...<<<<<........>>>>>))<
<<<.<<<<.<<<....<<<....>>>...<.((<<<<<<...<<<<.<<<
<<<<.<<<<<.<<<<...[[..>>>>.><...<<<<<....<<<<<<...
.<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<......
>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>...>.....
>>>...>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<...
..>>>>..>>>>..<<<<.....<<<<<<<.<<.........<.....<<
<<<....<....>.....>>>>><<.<<<<<<<<<<<....>>>>>..>>
>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<....<<<<.....>>>>......>>>>>>>.........<<.<<<<
<<....<<<.....<<<<....>>>>.....>>>.>>>>..>>>>.<<<<
<<.......>>>>>>......<<..>>......>>.>>>>>>>..>..>>
.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<
<<<..<<<........<<<<<.<<<<<<..<<<<<.<<<<<<<<..<<<<
<<<<..>>>>>>>>...<<<<<.....<<<<..<<<<<....>>>>>...
.......))..<<<<<.....>>>>>..>>>>..>>>>>.....>>>>>>
>>..>>>>>.......<<<<<<.<<<<<<....>>>>>>>>...<<<<<<
<...<<<<<<.......>>>>>>.....<<......>>....>>>>>>>.
...<<<<.<.<<<.....>>>.>>>>><<<<....>>>.>>>>>.<<...
<<<<<<<..<<<<.))))))>>>>>>>>>>>.....>>..>>>>..>>>>
>>>.........<<<<<<...<<.......>>...>>>>>>.........
......<<<<...<<<<..<.<<<<<<<......>>>>>>>...>.<<<.
........>>>.....>>>>.......>>>>......<<<<<<<....>>
>.>>>>........>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<..
...............>>>>>.><<<<<...<<<<....<<<<<<<<<<]]
..>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.........
..>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<...
...<<.......<<<....>>>....>>........<<<<.....<<<.<
<<<<.......>>>>>.>>>....>>>>..............>>>>>.>>
>>>...<<<<<<<.............>>....<<<<<<<<<.<<<....<
<<<....<<<<<......>>>>>...>>>>...>>>....>>>>..>>>>
>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv5 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.86 Å
Binding residue
(original residue number in PDB)
G24 M25 R26 K27 N28 Q30 W32 K36 A38 F39 R40 K43 G44 W48 R51 R55 K62 I80 I83
Binding residue
(residue number reindexed from 1)
G4 M5 R6 K7 N8 Q10 W12 K16 A18 F19 R20 K23 G24 W28 R31 R35 K42 I60 I63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8pv5, PDBe:8pv5, PDBj:8pv5
PDBsum8pv5
PubMed37921038
UniProtG0SCP3

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