Structure of PDB 8i9x Chain Cz Binding Site BS01

Receptor Information
>8i9x Chain Cz (length=70) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGMRKNGQVWLPAKKAFRPTKGLTSWELRVKKRQEQAAMKAKEREMKEEK
EAERQKRIQAIKERRKKKEE
Ligand information
>8i9x Chain C1 (length=2658) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuaugcuuggauagggug
aagccagaggaaacucugguggaggcucgcugacgugcaagaucgucaaa
ucugagcaugggggcgaaagacuaaccaucuaguagcugguuaccgccga
aguuucccucaggauagcagugucgaccuucaguuuuaugagguaaagcg
aaugaacuuuaaauauguaagaagcccuuguuacuuaacugaacgugggc
auucgaauguaucgacacuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacgcgggguuaaggugccggaguggacgcucauc
agacaccacaaaaggcguuaguacaucuugacagcaggacgguggccaug
gaagucggaauccgcuaaggacuguguaacaacucaccugccgaauguac
uagcccugaaaauggauggcgcucaagcgucccacccauaccccgcccuc
aggguagaaacgaugcccugaggaguaggcggccguggaggucagugacg
aagccuagggcgugagcccgggucgaacggccucuagugcagaucuuggu
gguaguagcaaauacuucaaugagaacuugaaggaccgaaguggggaaag
guuccaugugaacagcgguuggacauggguuagucgauccuaagccauag
ggaaguuccguuucaaaggggcacucgugccccguguggcgaaagggaag
ccgguuaauauuccggcaccuggauguggguuuugcgcggcaacgcaacu
gaacgcggagacgacggcgggggccccgggcagaguucucuuuucuucuu
aacggucuaucacccuggaaacaguuugucuggagauaggguuuaauggc
cggaagagcccgacacuucugucggguccggugcgcucucgacgucccuu
gaaaauccgcgggagggaauaauucucacgccaggucguacucauaaccg
cagcagguccccaaggugaacagccucugguugauagaacaauguagaua
agggaagucggcuccguaacuugguacggacaggggaaucugcgagauuc
ccacugucccuaucuacuaucuagcgaaaccacagccaagggaacgggcu
uggcaaaaucagcggggaaagaagacccuguugagcuugacucuaguuug
acauugugaaaagacauaggagguguagaauaggugggagcuucggcgcc
agugaaauaccacuacuccuauuguuuuuuuacuuauucaaugugaagac
auugucagguggggaguuccuuuagucccucgaaauuugaggcuagagga
gaaaaguuaccacagggauaacuggcuuguggcggccaagcguagcgacg
ucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauucgguaa
gcguuggauuguucacccacuaauagggaacgugagcuggaccgucguga
gacagguuagucccuacugaugaacucgucgcaaugguaauucagcuuag
uacgagaggaaccgcugauucagauaauugguuuuugcgguuguccgacc
gggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccucua
agucagaauccaugccagaacgcgacgauacuacccgcacguuguagacg
uauaagaauaggcuccggccucguauccuagcaggcgauuccuccgccgg
ccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgcgg
gaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaagca
guagaguagccuuguuguuacgaucugcugaggguaagcccuccuucgcc
uagauuuc
........................<<<<<<.....<<....>>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>>.<<.<..<<<<<<<...<.<<<<<<<<<..<<<<.
..<<<<<<<....>>>>>>>...>.>>>..<<<<<........>>>>>..
>>>>>>>>>>.<<.<....>.>>.>>>>>>>.....>.>>...<<<<<..
..<.<<<....>>>.><<<<<<<<<<....<<.<<<<<<<.....<<<..
......>>.>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<...<<<((......<<<<<<.....
.<..........<<<.<<<<<<<<<<.......<<<<<.<<<...<<...
......>>...>>>.........<<......>>...>>>>>...>>>>>>
>>>>>>>...........)).>....>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<
...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<
<<....>>>........<<<<<......>>>>>....>>>....>>...<
<<<<........>>>>>))<<<<.<<<<.<<<....<<<....>>>....
...<<<<<<...<<<<.<<<<<<<<<<<<<.<<<<...((..>>>>.><.
..<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>
>>....><<<<<<<<....>>>>>>>>>>>>.>.>>>>>>>.>>>>....
.....>>>>>>.........>>>...>>>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<.
<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>>.>>>>>
>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<........>>
>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.<<<<<
<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....>>...
.........>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>>>...
..>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>>.
...>>>>>.>.>>>>>>.............<<<<<<...<<...>>...>
>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>>>>>.
..>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<<....
>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<....
.............>>>>>.><<<<<...<<<<....<<<<<<<<<<))..
>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........
>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<.....
.<<.......<<<<..>>>>....>>........<<<<.....<<<.<<<
<<.......>>>>>.>>>....>>>>..............>>>>>.>>>>
>...<<<<<<<.............>>....<<<<<<<<<.<<<....<<<
<.<..<<<<<......>>>>>..>>>>>...>>>....>>>>..>>>>>.
..>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9x Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
G24 M25 R26 K27 N28 Q30 W32 K36 K37 A38 F39 R40 T42 K43 W48 R51 R55 K62
Binding residue
(residue number reindexed from 1)
G2 M3 R4 K5 N6 Q8 W10 K14 K15 A16 F17 R18 T20 K21 W26 R29 R33 K40
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8i9x, PDBe:8i9x, PDBj:8i9x
PDBsum8i9x
PubMed37129998
UniProtG0SCP3

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