Structure of PDB 8i9w Chain Cz Binding Site BS01

Receptor Information
>8i9w Chain Cz (length=70) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGMRKNGQVWLPAKKAFRPTKGLTSWELRVKKRQEQAAMKAKEREMKEEK
EAERQKRIQAIKERRKKKEE
Ligand information
>8i9w Chain C1 (length=2163) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuauaugggggcgaaaga
cuaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcagu
gucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaag
aagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacuag
ugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcg
ggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguuag
uacaucuugacagcaggacgguggccauggaagucggaauccgcuaagga
cuguguaacaacucaccugccgaauguacuagcccugaaaauggauggcg
cucaagcgucccacccauaccccgcccucaggguagaaacgaugcccuga
ggaguaggcggccguggaggucagugacgaagccuagggcgugagcccgg
gucgaacggccucuagugcagaucuuggugguaguagcauagaacaaugu
agauaagggaagucggcuccguaacuugguacggacaggggaaucugcga
gauucccacugucccuaucuacuaucuagcgaaaccacagccaagggaac
gggcuuggcaaaaucagcggggaaagaagacccuguugagcuugacucua
guuugacauugugaaaagacauaggagguguagaauaggugggagcuucg
gcgccagugaaauaccacuacuccuauuguuuuuuuacuuauucaaugug
aagacauugucagguggggaguuccuuuagucccucgaaauuugaggcua
gaggagaaaaguuaccacagggauaacuggcuuguggcggccaagcguag
cgacgucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauuc
gguaagcguuggauuguucacccacuaauagggaacgugagcuggaccgu
cgugagacagguuagucccuacugaugaacucgucgcaaugguaauucag
cuuaguacgagaggaaccgcugauucagauaauugguuuuugcgguuguc
cgaccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgc
cucuaagucagaauccaugccagaacgcgacgauacuacccgcacguugu
agacguauaagaauaggcuccggccucguauccuagcaggcgauuccucc
gccggccucgaaguggccgucgguaauucgcguauugcaauuuagacacg
cgcgggaucaaauccuuugcagacgacuuagaugugcgaaaggguccugu
aagcaguagaguagccuuguuguuacgaucugcugaggguaagcccuccu
ucgccuagauuuc
........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.....<.<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>....>.>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<....<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<...<<<<<<...<.<<>>>.<<.<....>.
>>.>>>>>>......>.>>...<<<<<....<.<<<....>>>.><<<<<
<<<<<....<<.<<<<<<<.....<<<........>>.>.....>>>>>.
..<<<<.<<<<.<......>>>>>.>>>>.....>>>>..>>>>>>>>.>
>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<
<<<<...<<<.(......<<<<<<.....<<..........<<<.<<<<<
<<<<<.......<<<<<.<<<...<<.........>>...>>>.......
..<<......>>...>>>>>...>>>>>>>>>>>>>...........)..
>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>
>>....>>>>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>>
>>...>>>>>>>>>>........>>>>>><<.....<<.<<<<.....<<
<<<<.<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>>.
>>>>>>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<.....
...>>>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.
<<<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....
>>............>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>
>>.....>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>
>>>>....>>>>>.>.>>>>>>.............<<<<<<...<<...>
>...>>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>
>>>>...>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<
<....>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<
<.................>>>>>.><<<<<...<<<<....<<<<<<<<<
<....>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<......
.....>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<
......<<.......<<<<..>>>>....>>........<<<<.....<<
<.<<<<<.......>>>>>.>>>....>>>>..............>>>>>
.>>>>>...<<<<<<<.............>>....<<<<<<<<<.<<<..
..<<<<....<<<<<......>>>>>...>>>>...>>>....>>>>..>
>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8i9w Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G24 M25 R26 K27 N28 Q30 W32 L33 K36 K37 A38 F39 R40 T42 K43 W48 R51 R55 K62
Binding residue
(residue number reindexed from 1)		G2 M3 R4 K5 N6 Q8 W10 L11 K14 K15 A16 F17 R18 T20 K21 W26 R29 R33 K40
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9w, PDBe:8i9w, PDBj:8i9w
PDBsum8i9w
PubMed37129998
UniProtG0SCP3

[Back to BioLiP]