Structure of PDB 8i9v Chain Cf Binding Site BS01

Receptor Information
>8i9v Chain Cf (length=59) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDESLLKKALKRKEARKKKSEREWKERIKAVEQSKQERQRKREENIRKRR
EEKLARKAG
Ligand information
>8i9v Chain C1 (length=2152) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaaguga
acguaggugagagcuucggcgcaucaucgaccgauccugauguauucgga
uggauuugaguaggagcguuaagccuuggacccgaaagauggugaacaac
caucuaguagcugguuaccgccgaaguuucccucaggauagcagugucga
ccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaagaagcc
cuuguuacuuaacugaacgugggcauucgaauguaucgacacuagugggc
cauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcgggguu
aaggugccggaguggacgcucaucagacaccacaaaaggcguuaguacau
cuugacagcaggacgguggccauggaagucggaauccgcuaaggacugug
uaacaacucaccugccgaauguacuagcccugaaaauggauggcgcucaa
gcgucccacccauaccccgcccucaggguagaaacgaugcccugaggagu
aggcggccguggaggucagugacgaagccuagggcgugagcccgggucga
acggccucuagugcagaucuuggugguaguagcaaauuugauagaacaau
guagauaagggaagucggcuccguaacuugguacggacaggggaaucugc
gagauucccacugucccuaucuacuaucuagcgaaaccacagccaaggga
acgggcuuggcaaaaucagcggggaagacccuguugagcuugacucuagu
uugacauugugaaaagacauaggagguguagaauaggugggagcuucggc
gccagugaaauaccacuacuccuauuguuuuuuuacuuauucaauugaag
acauugucagguggggaguuccuuuagucccucgaaauuugaggcuagag
gagaaaaguuaccacagggauaacuggcuuguggcggccaagcguucaua
gcgacgucgcuuuuuggaugucggcucuuccuaucauaccgaagcagaau
ucgguaagcguuggauuguucacccacuaauagggaacguggaccgucgu
gagacagguuagucccuacugaugaacucgucgcaaugguaauucagcuu
aguacgagaggaaccgcugauucagauaauugguuuuugcgguuguccga
ccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccuc
uaagucagaauccaugccagaacgcgacgauaacccgcacguagacguau
aagaauaggcuccggccucguauccuagcaggcgauuccuccgccggccu
cgaaguggccgucgguaauucgcguauugcaaagacacgcgcgggaucaa
auccuuugcagacgacuuagaugugcgaaaggguccuguaagcaguagag
uagccuuguuguuacgaucugcugaggguaagcccuccuucgccuagauu
uc
........................<<<<<<.....<......>......>
>>>>.>...<.....<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>....>.............................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<<....<<.<<<<<<<<<<.<<.<<<
<<<....>>>>>>>>...>>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<...<<<<
<<<<<.<<<<..<<<...<<<<.....>>>>...>>>...<<....>>..
.....<<<<<..<<....>>...>>>>>.<<<<<<<<....<....>...
.>>>.>>>.>>....>>>>.>>>>>>>>>.<<.<..<<<<<<<.....>>
>>>>...>..>.>>...<<<<<....<.<<<....>>>.><<<<<<<<<<
....<<.<<<<<<<.....<<<........>>.>.....>>>>>....<<
..<<<<.<......>>>>>.>>.......>>>>..>>>>>>>>.>>..<<
<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<.
..<<<(((.....<<<<<<.....<<..........<<<.<<<<<<<<<<
.......<<<<<.<<<...<<.........>>...>>>.........<<.
.....>>...>>>>>...>>>>>>>>>>>>>..........))).>>...
>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>>>...
.>>>>>.<.<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...
>>>>>>>>>>..>.....>>>>>><<.....<<........<<<<.....
<<<<<<.<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>
>.>>>>>>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<...
.....>>>>>....<<<<<.<<<.....<<<<<<.<<<<<<.<<<<<.<<
<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..........
............>>>>>.>>>>>>>.>>>>>>>>>>...<<<<..>>>>.
....>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>
>....>>>>>.>.>>>>>>.............<<<<<<...<<.......
>>...>>>>>>.....((........<<<<<<..<.<<<<<<<......>
>>>>>>...>.<<<.....))..>>>.....>>>>>..>...<<<<<<..
..>>>.>>>.....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<..
...............>>>>>.><<<<<...<<<<....<<<<<<<<<<..
..>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.........
..>>>>>...>>>>.>>>>....>>>>>>>...<<<<<.<<.......<<
.......<<<<..>>>>....>>........<<<<.....<<<.<<<<<.
......>>>>>.>>>....>>>>..............>>.>>>>>...<<
<<<<<.............>>....<<<<<<<<<.<<<....<<<<....<
<<<<......>>>>>...>>>>...>>>....>>>>..>>>>>...>>>>
>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9v Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K502 K504 S505 W509 R512 K520 E522 R523 K526 R527 E529 N530 R532 R534 K538 R541
Binding residue
(residue number reindexed from 1)		K17 K19 S20 W24 R27 K35 E37 R38 K41 R42 E44 N45 R47 R49 K53 R56
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
Biological Process
GO:0042273 ribosomal large subunit biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9v, PDBe:8i9v, PDBj:8i9v
PDBsum8i9v
PubMed37129998
UniProtG0S2I7

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