Structure of PDB 6rxv Chain Cf Binding Site BS01

Receptor Information
>6rxv Chain Cf (length=174) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GISRDSRHKRSHTGAKRAFYRKKRAFELGRQPANTRIGPKRIHIVRTRGG
NHKYRALRLDSGNFAWGSEGCTRKTRIIGVVYHPSNNELVRTNTLTKSAV
VQIDAAPFRQWYEAHYGQPLGRAAHGKVDPALEKQFEAGRLYAIISSRPG
QSGRADGYILEGEELAFYQRKLHK
Ligand information
>6rxv Chain C1 (length=1575) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guuggggaagcccuagcggcugaaccucucggucgggccuccucuugggg
cgccuaggcggugucuucgggucgcgugcagccucccguccucgccugcc
gacagcgcucuggggaauucaggaggggaaagcagaugugccccgcggcg
agacuggcgcaccgccggacgagcugcuggggcacgcggguacgcuagcc
gcacgauaguuaccugguugauucugcuagucauaugcuugucucaaaua
agccaugcgucuaaguauaagcaauuauacagcgaaacugcgaauggcuc
auuaaaucaguuaucguuuauuugauaguaccuuacuacauggauaaccg
ugguaauucuagagcuaauacaugcugaaaaucccgacuucggaagggau
guauuuauuagauuaaaaaccaaugcccuucggggcggugauucauaaua
acuucucgaaucgcacggccuuggccggcgaugguucauucaaauuucug
cccuaucaacuuucgacggcuggguauuggccagccguggugacaacggg
uaaggguuagggcucggagaaggagccugagaaacggcuacuacauccaa
ggaagggcaggcgcgcaaauuacccaaucccgacacggggagguagugac
aauaaauacugauacagggcucuuucgggucuuguaauuggaaugaguac
aauuuaaaucccuuaacgaggaacaauuggagggcaagucuggugccagc
agccgcgguaauuccagcuccaauagcguauauugcucguaguugaaccu
gggccuagcccgccgguccgccucaccgcgugcacuggcugggcugggcc
ugauuaauagggacagucgggggcgucaguauucaauugucagaggugaa
auucuuggauuuauugaagacuaacaacugcgaaagcauucgccaaggau
guuuucauuaaucaggaacguaaacuauuagggaucggacggcguuuauu
uuugacccguucggcaccuuacgauaggaguauggucgcaaggcugaaaa
auugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
ggucuccguaggugaaccugcggag
<<<<<<.<<<<<<<<....>>>>>>>>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<..<<...<<<<.....>>>>...>>..>>>>>.>>>>>>>>.....<<<
<<<...<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>
....>>>>>>...........................<<<<<<<<<<<<.
.<.<<<<<.....>>>>>.>..>>>>>.>>>>>>><<<<.........>>
>>...........................<<.<<<<<<...<.<<.....
.<<<.<<<<<....<<....<<.........>>...>>.>>......<<<
.......<<<..<<..<<....<<<...............<<.....<..
<<.......>>..>......>>........<<<<<..........>>>>>
<...<<<<<<..............<<<<....>>>>.........>>>>>
>.....>...<<<<.<<<<....>>>>>>>>....>>>...>>>>..>>>
.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>
...<<<<....>>>>.>>>.<<.<<<<........>>>>.>>.<.<<<..
>>>.>.>>>>>>.........<<<...<<<<.....>>>.>>>>...>..
.>.>....<<<<<<<<<<<<<<....>>>>>>>>>.>>>>>.....<<..
<...........>..>>.........<<<<<<.......<<<....>>>.
.................>>>>>>..>>>>>>>>.<.<<...<<<.<<...
<<<<<<<<<<<<<<<<<.<<<......>>>...>>>>>>.>>>>>>>>>>
>..>>....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<.....
.>>>......>.>>>>>>.>>>.......<<....>>...>>>>..>>.>
>>.>>>...>>>...>>.>...........<<..<<<<<<<<.<<<....
...>>>>>>>>>>>..>>................................
...<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>..<<<<.<<......>>.>>>>
...<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB6rxv Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.0 Å
Binding residue
(original residue number in PDB)
R5 H9 K10 R11 T14 G15 A16 F20 K23 R25 A26 F27 L29 G30 R31 P33 K41 I43 R47 T48 R49 G50 K54 Y55 R56 N64 A66 T73 P85 S86 N87 K98 S99 S175 R176 G178 Q179 R182
Binding residue
(residue number reindexed from 1)
R4 H8 K9 R10 T13 G14 A15 F19 K22 R24 A25 F26 L28 G29 R30 P32 K40 I42 R46 T47 R48 G49 K53 Y54 R55 N63 A65 T72 P84 S85 N86 K97 S98 S147 R148 G150 Q151 R154
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6rxv, PDBe:6rxv, PDBj:6rxv
PDBsum6rxv
PubMed31378463
UniProtG0RY45

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