Structure of PDB 8jiv Chain Ce Binding Site BS01

Receptor Information

>8jiv Chain Ce (length=125) Species: 4565 (Triticum aestivum)

AVPLLTRKIVKKRVKHFKRAHSDRYIGLKQSWRRPKGIDSRVRRKFKGCT
LMPNIGYGSDKKTRHYLPNKFKKFVVHNVSELELLMMHNRTYCAEIAHNV
STKKRKDIVERAAQLDIVVTNKLAR

Ligand information

>8jiv Chain Aa (length=2863)

gcgaccccaggucaggcgggacuacccgcugaguuuaagcauauaaauaa
gcggaggagaagaaacuuacaaggauuccccuaguaacggcgagcgaacc
gggagcagcccagcuugagaaucgggcggcugugccguccgaauuguagu
cuggagaggcguccugcgacggaccgggcccaaguccccuggaaaggggc
gccugggagggugagagccccguccggcccggacccugucgcgaggcgcc
ucaacgagucggguuguuugggaaugcagcccaaaucgggcgguagacuc
cguccaaggcuaaauacaggcgagagaccgauagcgaacaaguaccgcga
gggaaagaugaaaaggacuuugaaaagagagucaaaagugcuugaaauug
ccgggagggaagcggaugggggccggcgaugcgccccggccguaugcgga
acggcugguccgccgcucggcucgggguguggacuguugucggccgcgcc
ggcggccaaagcccgggggcccuaggugcccccgguggccgucgucggca
cggccgcgcgccuaaaggcgugucccucggggcacugcgcugcaacggcc
ugcgggcuccccauccgacccgucuugaaacacggaccaaggagucugac
augcgugcgagucgacggguucugaaaccugggaugcgcaaggaagcuga
cgagcgggaggcccugggccgcaccgcuggccgacccugaucuucuguga
aggguucgaguuggagcacgccugucgggacccgaaagauggugaacuau
gccugagcggggcgaagccagaggcucugguggaggcucgaagcgauacu
gacgugcaaaucguucgucugacuuggguauaggggcgaaagacuaaucg
aaccaucuaguagcugguucccuccgaaguuucccucaggauagcuggag
cccaacgaguucuaucagguaaagccaaugauuagaggccuauucucaaa
cuuuaaauagguaggauggcgcggcugcuucggugagccgugccauggaa
ucgggcuccaagugggccauuuuugguaagcagaacuggcgaugcgggau
gaaccggaagccggguuacggugcccaacugcgcgcuaaccuagaaccca
caaaggguguuggucgaacuagccccgaaaauggauggcgcugaagcgcg
cgacccacacccggccaucugggcgagcgccaugccccgaugaguaggag
ggcgcggcggccgcugcaaaacccggggcgcgagcccgggcggagcggcc
gucggugcagaucuuggugguaguagcaaauauucaaaugagaacuuuga
aggccgaagaggagaaagguuccaugugaacggcacuugcacauggguaa
gccgauccuaagggacgggguaaccccggcagauagcgcacgcgccccga
aagggaaucggguuaagauuucccgagccgggauguggcgguugacggcg
acguuaggaaguccggagacgccggcgggggccucgggaagaguuaucuu
uucugcuuaacggccugccaacccuggaaacgguucagccggagguaggg
uccaguggccggaagagcaccggguguccggugcgcccccggcggcccau
gaaaauccggaggaccgccguucacgcccggucguacucauaaccgcauc
aggucuccaaggugaacagccucuggccaauggaacaauguaggcaaggg
aagucggcaaaacggauccguaacuucgggaaaaggauuggcucugagga
ccgacucagaacugguacggacaaggggaauccgacuguuuaauuaaaac
aaagcauugcgaugguccucgcggaugcugacgcaaugugauuucugccc
agugcucugaaugucaaagugaagaaauucaaccaagcgcggguaaacgg
caagguagccaaaugccucgucaucuaauuagugacgcgcaugaauggau
uaacgagauucccacugucccugucuacuauccagcgaaaccacagccaa
gggaacgggcuuggcggaaucagcggggaaagaagacccuguugagcuug
acucuaguccgacuuugugaauacuuauuccgugggucggaaguuuuggc
uccaaggccggccgauccgggcggaagacauugucagguggggaguuugg
cuggggcggcacaucuguuaaaagauaacgcagguguccuaagaugagcu
caacgagaacagaaaucucguguggaacaaaaggguaaaagcucguuuga
uucugauuuccaguacgaauacgaaccgugaaagcguggccuaucgaucc
uuuagcuucggaguuugaagcuagaggugucagaaaaguuaccacaggga
uaacuggcuuguggcagccaagcgauagcgacguugcuuuuugauccuuc
gaugucggcucuuccuaucauugugaagcagaauucaccaaguguuggau
uguucacccaccaauagggaacgugagcuggguuuagaccgucgugagac
agguuaguuuuacccuacugaugacagugucgcgauaguaauucaaccua
guacgagaggaaccguugauucacacaauuggucaucgcgcuugguugaa
aagccaguggcgcgaagcuaccgugugccggauuaugacugaacccucua
agucagaauccaagcuagcaugcgacgccucgacccacguuaggcccaag
ggcccgugggccgaagugcagcucccuucccgaauccuuugcagacgacu
uaagacggggcauuguaaguggcagagugacgauccacugagauccagcc
ccgucgcauucgu

........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<.......<.....>......
>>>>>..<<<....<......<<<<<<<<<...>>>>>>>>>......>.
.....<<<<<<<<.<<<<<<<<.<<<<<<<.....<<<<......>>>>.
((......<<<.....))>>>....>>>>>>>...>>>>>>>>.>>>>>>
>>........<<<<<<<........>>>>>>>.....<<<<<..((((((
>>>>>..>>>..................................<<....
>>...............<<<<....>>>>.....................
............<<<<<<<<<<<<......<.<<<<<<.<.......<<.
..<.>...>>........>..>.>>>>>.>.<.<<<<<<......<<...
.<..<......<..<<..<.......>.>>...>.....>..>....>>.
.......<<.<.<....>.>....<......>......>>..>>>>>>.>
....>>>.>>>>>>>>>..<<<<........>>>><<<<<<....<<<<<
<.<<<<<<..<<...<<<<<<....>>>>>>....>>...<<....>>..
..<<<<<..<<<<<.>>>>>...>>>>><<<<<<<<.....<....>...
..>>.>>>.>>>...>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<.>>>>>>>.....>>>...<<<<.<<.
<<........>>>>>>>>....>>>>>>>>>...<<.......>>.....
.>>>>>>...>..>.>>..<<<<<<....<.<<<....>>>.><<<<<<<
.<<..<<<.<<<<<<<.....<<<....<<<..<.<<..>>.>..>>>..
>>.>.....>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>
>>>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<...
...>>>...<<<<<<<...<<<(((.....<<<<<<.......<......
....<<<.<<<<<<...>>>>>>>>>..........))).>....>>>>>
>.>>>...>>>>>>><<<<.<<<<.........>>>>.>>>>....>>>>
>><.<<<<<<<<<<.......<<<.<<<<....>>>>>>>....>>>>>>
>>>>..>.....>>>>>><<.....<<.....<<<<<<.......>>>>>
><<<<<....<<<<<.<<...<<<<<....<<.....>>..>>>>>....
((<<<<<<...<<<...<<<....>>>........<<<..>>>..>>>..
..>>...<<<<<.........>>>>>))<<<<.<<<<<<<<...<<<...
.>>>...<...<<<<<<...<<<<.<<<<<<<.<<<<<.<<<<...[[..
>>>>.><...<<<<<.....<<<<<<....<<<<...>>>>....>>>>>
>.....>>>>>....><<<<<.>>>>>>>>>...>>>>>>>.>>>>....
.....>>>>>>...>..>>>>.>>>>>>>>>>>>..>>.....<<.....
.>>>>>>>.<<<<.....>>>>.>>>>>..<<<<.....<<<<<<<.<<.
........<.....<<<<<....<<..>>.....>>>>><<.<<<<<<..
....>>>>>>.>>............<<<<<<<<<..<<<.........>>
>..<<<<<<<....<<<<....>>>>......>>>>>>>...<<..<<<.
.<<<<<<....<<<.....<<<<....>>>>.....>>>.>>>>..>>>>
>......<...........<<<<<.......>>>>>.....>.....>>.
...>>.>>>>>>>..>..>>.>>>>>>>..>>>>>>....>>....<<<<
<........>>>>>....<<<<<..<<<.<<......<<<<.<<<<<<..
<<<<<.<<<.<<<...<<<..>>>...<<<<<.....<<<<.........
.....<<<..>>>..>>>>..>>>>>......>>>.>>>..>>>>>...<
<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...
<<<..<<<<.......>>>>..>>>.<<<....>>>.>>))).......<
<<<<<<<<<.))))))>>>>>>>>>>..........>>>>..>>>>>>..
.....<<.<.<.<<<<<<...<<....>>...>>>>>>...>>.>.>...
....<<<<<..<<<<<..<<<.<<<<<......>>>>>...>>>.<<<..
.......>>>.....>>>>>......>>>.>>....<<<<<<<....>>>
.>>>>....>>..>>>.>>>>>....<<<<<<<..<<<<...<<<<<...
..............>>>>>..<<<<<...<<<<....<<<<<<<<<.]].
..>>>>..>>>>>...>>>>..>>>>>..<<<...<<<<<..........
>>>>>...>>>..>>>>....>>>>>>>.....<<.......<..>....
>>.............................<<<<..<............
.>.<<<<<<<.<<<....<<<<.<..<<.>>..>>>>>...>>>....>>
>>>>>..>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8jiv Cryo-EM structure of wheat ribosome reveals unique features of the plant ribosomes.
• Resolution: 2.84 Å
• Binding residue (original residue number in PDB): A2 K12 K13 R14 V15 K16 F18 R20 H22 D24 R25 Y26 I27 G28 L29 W33 R34 R35 G38 I39 D40 S41 R42 R44 R45 K46 F47 K48 G49 P54 N55 I56 G57 Y58 G59 S60 D61 K62 R65 H66 P69 K74 H78 N79 E96 A98 H99 N100 S102 T103 K105 R106 V119 N122 A125 R126
• Binding residue (residue number reindexed from 1): A1 K11 K12 R13 V14 K15 F17 R19 H21 D23 R24 Y25 I26 G27 L28 W32 R33 R34 G37 I38 D39 S40 R41 R43 R44 K45 F46 K47 G48 P53 N54 I55 G56 Y57 G58 S59 D60 K61 R64 H65 P68 K73 H77 N78 E95 A97 H98 N99 S101 T102 K104 R105 V118 N121 A124 R125

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8jiv, PDBe:8jiv, PDBj:8jiv
• PDBsum: 8jiv
• PubMed: 38458197
• UniProt: A0A3B6SDD9