Structure of PDB 6hiw Chain Ca Binding Site BS01

Receptor Information
>6hiw Chain Ca (length=592) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RYPFNKRGPREHKSWKHHVLTEPPKPLQWRDPKVWTRDLSVMKSFDAPQW
DLWQSRPRSEDMDEALQPFMDMPKSLKDRRYDIPWWANPFGAWYLQNILS
LELLKLKSKTNAEKIATYRSYMRSLASGKDNTMSDDDVIRNIIKERWKTL
EFGDRNAGYPCTFGDYIQFLNEWFKSLDEEGMQRLREHFDRRIRPLLAVM
SPVDILWLEALTQNSPHNKEQLQRKIAFQTSLGTPEFFDMSKRLRYEINE
DYKVRDELGPELFALWSKAPERWPPERLSKMYGLDFTLVRKILVWHHFKA
CYDACVEPDWSLPKRLFALEWIRDVRARKHGLFYGKMRFAEQKITFYSDR
FLFRDLVNRREASYANVWEMDDPYRFLQTEQDYEDYWGDNYDVYRRMFPE
MIGRTGEPVQQYGQMPIWAGPHRQHANKSEHNWMFAEIGVNVGHEALKKL
ELDPTNEKRRRFVIRQPDGTLRSAKMSEMRAWYWKEEWADFRFWAPQMEW
GIENTPSQEQYQEHVPDTTDADFRKQRRIQSRPVKWFYESHYTRTGSFAG
FQPLRFMQRRTEREVRWPDVINAAVQIQKRKPAAYIFKAIPE
Ligand information
>6hiw Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
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....................<<<.......<<<<..............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution3.37 Å
Binding residue
(original residue number in PDB)		R10 Y11 P12 F13 K15 P18 R19 H339 K352 S357 R359 R363 R432 H523 Q567 R568 R569 T570 E571 R572 E573 V574 R575 W576 P577 V579 N581 Q585 Q587 K588 R589 K590 Y594 K597
Binding residue
(residue number reindexed from 1)		R1 Y2 P3 F4 K6 P9 R10 H330 K343 S348 R350 R354 R423 H514 Q558 R559 R560 T561 E562 R563 E564 V565 R566 W567 P568 V570 N572 Q576 Q578 K579 R580 K581 Y585 K588
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum6hiw
PubMed30213880
UniProtQ38DR3

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