Structure of PDB 8i9w Chain CX Binding Site BS01

Receptor Information
>8i9w Chain CX (length=88) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VYSEKELGIPQLNTVTPVGVTKPKGKKKGKVFVDDRESMNTILAMVEAEK
QGQIESKIMRARQLEEIREARRIEAEKKEAERKALLEN
Ligand information
>8i9w Chain C1 (length=2163) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuauaugggggcgaaaga
cuaaccaucuaguagcugguuaccgccgaaguuucccucaggauagcagu
gucgaccuucaguuuuaugagguaaagcgaaugaacuuuaaauauguaag
aagcccuuguuacuuaacugaacgugggcauucgaauguaucgacacuag
ugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcg
ggguuaaggugccggaguggacgcucaucagacaccacaaaaggcguuag
uacaucuugacagcaggacgguggccauggaagucggaauccgcuaagga
cuguguaacaacucaccugccgaauguacuagcccugaaaauggauggcg
cucaagcgucccacccauaccccgcccucaggguagaaacgaugcccuga
ggaguaggcggccguggaggucagugacgaagccuagggcgugagcccgg
gucgaacggccucuagugcagaucuuggugguaguagcauagaacaaugu
agauaagggaagucggcuccguaacuugguacggacaggggaaucugcga
gauucccacugucccuaucuacuaucuagcgaaaccacagccaagggaac
gggcuuggcaaaaucagcggggaaagaagacccuguugagcuugacucua
guuugacauugugaaaagacauaggagguguagaauaggugggagcuucg
gcgccagugaaauaccacuacuccuauuguuuuuuuacuuauucaaugug
aagacauugucagguggggaguuccuuuagucccucgaaauuugaggcua
gaggagaaaaguuaccacagggauaacuggcuuguggcggccaagcguag
cgacgucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauuc
gguaagcguuggauuguucacccacuaauagggaacgugagcuggaccgu
cgugagacagguuagucccuacugaugaacucgucgcaaugguaauucag
cuuaguacgagaggaaccgcugauucagauaauugguuuuugcgguuguc
cgaccgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgc
cucuaagucagaauccaugccagaacgcgacgauacuacccgcacguugu
agacguauaagaauaggcuccggccucguauccuagcaggcgauuccucc
gccggccucgaaguggccgucgguaauucgcguauugcaauuuagacacg
cgcgggaucaaauccuuugcagacgacuuagaugugcgaaaggguccugu
aagcaguagaguagccuuguuguuacgaucugcugaggguaagcccuccu
ucgccuagauuuc
........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.....<.<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>....>.>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<.<....>.>>>><<<<<<....<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<...<<<<<<...<.<<>>>.<<.<....>.
>>.>>>>>>......>.>>...<<<<<....<.<<<....>>>.><<<<<
<<<<<....<<.<<<<<<<.....<<<........>>.>.....>>>>>.
..<<<<.<<<<.<......>>>>>.>>>>.....>>>>..>>>>>>>>.>
>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<
<<<<...<<<.(......<<<<<<.....<<..........<<<.<<<<<
<<<<<.......<<<<<.<<<...<<.........>>...>>>.......
..<<......>>...>>>>>...>>>>>>>>>>>>>...........)..
>>...>>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>
>>....>>>>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>>
>>...>>>>>>>>>>........>>>>>><<.....<<.<<<<.....<<
<<<<.<<<<<<<<....<<<<<<.<..>.>>>>>>...<<<<<<<<<>>.
>>>>>>>>>>.>>>>>>>>>>>..>>>>>>....>>....<<<<<.....
...>>>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.
<<<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....
>>............>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>
>>.....>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>
>>>>....>>>>>.>.>>>>>>.............<<<<<<...<<...>
>...>>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>
>>>>...>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<
<....>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<
<.................>>>>>.><<<<<...<<<<....<<<<<<<<<
<....>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<......
.....>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<
......<<.......<<<<..>>>>....>>........<<<<.....<<
<.<<<<<.......>>>>>.>>>....>>>>..............>>>>>
.>>>>>...<<<<<<<.............>>....<<<<<<<<<.<<<..
..<<<<....<<<<<......>>>>>...>>>>...>>>....>>>>..>
>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9w Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G87 K88 K89 K90 K92 F94
Binding residue
(residue number reindexed from 1)		G25 K26 K27 K28 K30 F32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0008298 intracellular mRNA localization
GO:0042273 ribosomal large subunit biogenesis
GO:0051028 mRNA transport
Cellular Component
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i9w, PDBe:8i9w, PDBj:8i9w
PDBsum8i9w
PubMed37129998
UniProtG0SGJ0

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