Structure of PDB 8oeq Chain CW Binding Site BS01

Receptor Information
>8oeq Chain CW (length=178) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRAPRTYSKTYSVPKRPYESARLDAELKLAGEYGLKNKREIYRIGFQLSK
IRRAARDLLTRDEKDPKRLFEGNALIRRLVRIGVLSEDKMKLDYVLALKP
EDFLERRLQTQVFKLGLARSIHHARVLITQRHIAVGKQIVNIPSFTVRLD
SQKHIDFAHNSPYGGGRAGRVKRKNQGK
Ligand information
>8oeq Chain CM (length=1726) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaauaac
uuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucugc
ccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgggu
aacggggaauaaggguucgauuccggagagggagccugagaaacggcuac
cacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauaacgauacaggguuguaauuggaaugaguaca
auguaaauaccuuaacgaggaacaauuggagggcaagucuggugccagca
gccgcgguaauuccagcuccaaaagcguauauuaaaguuguugcaguuaa
aaagcucguaguugaaccuugggcuuggcuggccgguccuggacccagcc
gagccuuuccuucuggguagccauuuauggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggccuuugcucgaauauauuagcaug
gaauaauagaauaggacguuaugguucuauuuuguugguuucuaggacca
ucguaaugauuaauagggacggucggggguaucaguauucaguugucaga
ggugaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuacc
aaggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauc
agauaccgucguagucuuaaccauaaacuaugccgacuagggaucgguug
uuguucuuuuauugacgcaaucggcaccuuacgagaaaucaaagucuuug
gguucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
gaaacucaccagguccagacacaauaaggauugacagauugagagcucuu
ucuugauuuugugggugguggugcauggccguucuuaguugguggaguga
uuugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauagu
gcugcuagcauuugcugguauagucacuucuuagagggacuaucgauuuc
aagucgauggaaguuugaggcaauaacaggucugugaugcccuuagacgu
ucugggccgcacgcgcgcuacacugacggagccagcgaguagccuuggcc
gagaggucugggaaaucuugugaaacuccgucgugcuggggauagagcau
uguaauuguugcucuucaacgaggaauuccuaguaagcgcaagucaucag
cuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuacua
ccgauugaauggcuuagugaggccuccggauugguuuagggaaccgagaa
gcuggucaaacuuggucauuuagaggaaguaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<.........((((.<<<....>>>..............>>>>>>.
....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.
<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>>>>
..>>>..>....>.>.....<<<<...<...>...>>>>......<<..<
...........>..>>.........<<<<<((......<<<<.....<<.
.))>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<[[..
...<.<<...<<<.<<....<<<<<<<<<<<<............>>>>>>
>>>>>>......<<......................>>.....<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........<<<..<<<<<<<<<.....))))....>>>>>>>>
>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<
<......>>>......>.>>>>>>..>>.......<<....>>...>>>>
...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<.
....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<
<..<<........>>.>>>>>>>>..>>>...<<..]]>>...>>.....
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}<<<<<.
<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<....<<<<<........<<.<<<........>>>.
>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.<<<<<....
>>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<
<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....<<<<<<...
..>>>>>>.......>>>>>.....>>.>>>.....>>>>>>>.....>.
>>>>>...>>.>>>>.>>>.....<<<<<<<......<<...<<<.<<<<
....>>>>.>>>....>>.......>>>>>>>...........<<<<<<.
.........>>>>>>..........>>>>>>....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<..<...<<<<<.......>>>>>...
>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<
<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)		P2 R3 R6 T7 Y8 S9 K10 T11 Y12 V14 K16 R17 Y19 K37 N38 K39 R40 R44 K51 F71 E72 A75 R78 R79 R82 R120 S121 H124 R126 Q131 H133 N142 I143 S145 F146 T147 R149 S152 Y164 G170 R171 K173 K175 N176
Binding residue
(residue number reindexed from 1)		P1 R2 R5 T6 Y7 S8 K9 T10 Y11 V13 K15 R16 Y18 K36 N37 K38 R39 R43 K50 F70 E71 A74 R77 R78 R81 R119 S120 H123 R125 Q130 H132 N141 I142 S144 F145 T146 R148 S151 Y163 G169 R170 K172 K174 N175
External links