Structure of PDB 6rxv Chain CW Binding Site BS01

Receptor Information
>6rxv Chain CW (length=382) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLTNPGPVPVYTVAGPSTARPLPDWLLRRRKRSAKYDPENLNNFELIQEF
EFEEASNCVRVSEDGNWIMSTGTYKPQFHVHNTRELSLSFSRHTNSENVT
FLLLSQDYSKSVHLQCDRTLEFHTPMGCHYSIRIPRFGRDLAYLRQSCEV
LVPAVGLSSDGSGYGEVFRLDLERGQFLRPWQVDVGEDEPGSGLQGSIHA
GAVNVAAVAENTHGLCAFGTSIGTVEFYDPRSKSRVAVLGNQDGEITALD
YSRDGLSLALGTSTGQIRIFDLRNPRPLLKKDQGMGLPIKNLIHLTTPTE
ERKLLSADKRIIKIWDEQSGDLWTSVEPLVDLNFVTHVPDSGMILTANEG
KQMHCFFIPNLGLAPRWCHFLDNLVHEMESEK
Ligand information
>6rxv Chain C1 (length=1575) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guuggggaagcccuagcggcugaaccucucggucgggccuccucuugggg
cgccuaggcggugucuucgggucgcgugcagccucccguccucgccugcc
gacagcgcucuggggaauucaggaggggaaagcagaugugccccgcggcg
agacuggcgcaccgccggacgagcugcuggggcacgcggguacgcuagcc
gcacgauaguuaccugguugauucugcuagucauaugcuugucucaaaua
agccaugcgucuaaguauaagcaauuauacagcgaaacugcgaauggcuc
auuaaaucaguuaucguuuauuugauaguaccuuacuacauggauaaccg
ugguaauucuagagcuaauacaugcugaaaaucccgacuucggaagggau
guauuuauuagauuaaaaaccaaugcccuucggggcggugauucauaaua
acuucucgaaucgcacggccuuggccggcgaugguucauucaaauuucug
cccuaucaacuuucgacggcuggguauuggccagccguggugacaacggg
uaaggguuagggcucggagaaggagccugagaaacggcuacuacauccaa
ggaagggcaggcgcgcaaauuacccaaucccgacacggggagguagugac
aauaaauacugauacagggcucuuucgggucuuguaauuggaaugaguac
aauuuaaaucccuuaacgaggaacaauuggagggcaagucuggugccagc
agccgcgguaauuccagcuccaauagcguauauugcucguaguugaaccu
gggccuagcccgccgguccgccucaccgcgugcacuggcugggcugggcc
ugauuaauagggacagucgggggcgucaguauucaauugucagaggugaa
auucuuggauuuauugaagacuaacaacugcgaaagcauucgccaaggau
guuuucauuaaucaggaacguaaacuauuagggaucggacggcguuuauu
uuugacccguucggcaccuuacgauaggaguauggucgcaaggcugaaaa
auugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
ggucuccguaggugaaccugcggag
<<<<<<.<<<<<<<<....>>>>>>>>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<..<<...<<<<.....>>>>...>>..>>>>>.>>>>>>>>.....<<<
<<<...<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>
....>>>>>>...........................<<<<<<<<<<<<.
.<.<<<<<.....>>>>>.>..>>>>>.>>>>>>><<<<.........>>
>>...........................<<.<<<<<<...<.<<.....
.<<<.<<<<<....<<....<<.........>>...>>.>>......<<<
.......<<<..<<..<<....<<<...............<<.....<..
<<.......>>..>......>>........<<<<<..........>>>>>
<...<<<<<<..............<<<<....>>>>.........>>>>>
>.....>...<<<<.<<<<....>>>>>>>>....>>>...>>>>..>>>
.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>
...<<<<....>>>>.>>>.<<.<<<<........>>>>.>>.<.<<<..
>>>.>.>>>>>>.........<<<...<<<<.....>>>.>>>>...>..
.>.>....<<<<<<<<<<<<<<....>>>>>>>>>.>>>>>.....<<..
<...........>..>>.........<<<<<<.......<<<....>>>.
.................>>>>>>..>>>>>>>>.<.<<...<<<.<<...
<<<<<<<<<<<<<<<<<.<<<......>>>...>>>>>>.>>>>>>>>>>
>..>>....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<.....
.>>>......>.>>>>>>.>>>.......<<....>>...>>>>..>>.>
>>.>>>...>>>...>>.>...........<<..<<<<<<<<.<<<....
...>>>>>>>>>>>..>>................................
...<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>..<<<<.<<......>>.>>>>
...<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxv Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		R30 R33 S34 K36 S90 F91 H94 R119 M127 R134 G194 L195 Q196
Binding residue
(residue number reindexed from 1)		R29 R32 S33 K35 S89 F90 H93 R118 M126 R133 G193 L194 Q195
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxv, PDBe:6rxv, PDBj:6rxv
PDBsum6rxv
PubMed31378463
UniProtG0S902|NOL10_CHATD Ribosome biogenesis protein ENP2 (Gene Name=ENP2)

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