Structure of PDB 4v6w Chain CW Binding Site BS01

Receptor Information
>4v6w Chain CW (length=130) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIGLCAFSGYKIYPGHGKTMVKIDGKSFTFLDKKCERSYLMKRNPRKVT
WTVLYRRKHRKGIEEEASKKRTRRTQKFQRAIVGASLAEILAKRNMKPEV
RKAQRDQAIKVAKEQKRAVKAAKKAAAPAP
Ligand information
>4v6w Chain B2 (length=1957) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auucugguugauccugccaguaguuauaugcuugucucaaagauuaagcc
augcaugucuaaguacacacgaauuaaaagugaaaccgcaaaaggcucau
uauaucaguuaugguuccuuagaucguuaacaguuacuuggauaacugug
guaauucuagagcuaauacaugcaauuaaaacaugaaccuuaugggacgu
gugcuuuuauuaggcuaaaaccaagcgaucgcaagaucguuauauugguu
gaacucuagauaacaugcagaucguauggucuuguaccgacgacagaucu
uucaaaugucugcccuaucaacuuuugaugguaguaucuaggacuaccau
gguugcaacggguaacggggaaucaggguucgauuccggagagggagccu
gagaaacggcuaccacaucuaaggaaggcagcaggcgcguaaauuaccca
cucccagcucggggagguagugacgaaaaauaacaauacaggacucauau
ccgaggcccuguaauuggaaugaguacacuuuaaauccuuuaacaaggac
caauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaa
uagcguauauuaaaguuguugcgguuaaaacguucguaguugaacuugug
cuucauacggguaguauacuauaccuuuauguauguaagcguauuaccgg
uggaguucuuauaugugaucauauguuccuccuauuuaaaaaccugcauu
agugcucuuaaacgaguguuauugugggccgguacuauuacuuugaacaa
auuagagugcuuaaagcaggcuucaaaugccugaauauucugugcauggg
auaaugaaauaagaccucuguucugcuuucauugguuuucagaucaagag
guaaugauuaauagaagcaguuugggggcauuaguauuacgacgcgagag
gugaaauucuuggaccgucguaagacuaacuuaagcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuagagguucgaaggcgauca
gauaccgcccuaguucuaaccauaaacgaugccagcuagcaauugggugu
agcuacuuuuauggcucucucagucgcuuccgggaaaccaaagcuuuuug
ggcuccgggggaaguaugguugcaaagcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
aaaacuuaccaggucgaacauaaguguguaagacagauugauagcucuuu
cucgaaucuaugggugguggugcauggccguucuuaguucguggagugau
uugucugguuaauuccgauaacgaacgagacucaaauauauuaaauagau
aucuucaggauuauggugcugaagcuuauguagccuucauucauguuggc
aguaaaaugcuuauuguguuugaauguguuuauguaaguggagccguacc
uguugguuugucccauuauaaggacacuagcuucuuaaauggacaaauug
cgucuagcaauaaugagauugagcaauaacaggucugugaugcccuuaga
uguccugggcugcacgcgcgcuacaaugaaaguaucaacguguauuuccu
agaccgagagguccggguaaaccgcugaaccacuuucaugcuugggauug
ugaacugaaacuguucacgaugaacuuggaauucccaguaagugugaguc
auuaacucgcauugauuacgucccugcccuuuguacacaccgcccgucgc
uacuaccgauugaauuauuuagugaggucuccggacgugaucacugugac
gccuugcguguuacgguuguuucgcaaaaguugaccgaacuugauuauuu
agaggaaguaaaagucguaacaagguuuccguaggugaaccugcggaagg
aucauua
...<<<<<...[[[[>>>>>[[[[.((((((................{{{
.{{{..<<....<<....<<.........>>...>>.>>...........
.....{{{.{{{..{{....[[[[..............<<.....<<.<<
<.....>>>.>>......>>..........<<<<<............>>>
>>[[..(((((.....<<<<<<<<.<<<<<....>>>>>...........
........)))))...]]...<<<<.<<<<.....>>>>>>>>...]]]]
...}}}}}.}}}.<<<....<<<....<<<<<<<<.......>>>>>>>>
>>>......>>>...<<<.<<<<....>>>>....>>>....<<.<<<..
........>>>.>>.<.<<....>>.>...}}}}}}.........<<<..
..<<<.....>>>..>>>...............<<<<<<<<<.<<<....
..>>>..>>>>>>.>>>...<..<<<.<...........>>.>>>.....
...<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>
..))))))]]]].........{{{{{.....[[[[...[[[.[[.....<
<<<.<<<<.<<<<<<<>>>>..>>.>....>>>>..>>>>....<<<<<<
.<<<<.....<<<<<<<<>>>>>>>>..>>>>..........<<<<<<.<
<<<<<<<......>>>>>>>>.>>>>>>>>>>>>..<<<<<<.<<.....
..<<...<.......>..<<<.......>>>....>>.......>>.>>.
.>>>>........((((((.(..(.......>>>>>>>>...)..)))))
)).....]]....<<<<..<<<<...<<<<..<<<.<<<<<<<<.<.<<<
......>>>.....>>>>>>>>>.>>>.......<<....>>...>>>>.
.>>>>.>.>>>...]]]...]]]]....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<.<.
.<<<<......>>>>.>.>>>>>..>>>...<<..}}>>...>>......
>>>.}}}.<<<......<<<<....>>>>....>>>..]]]]..<<<<<.
<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<...<<<<........<<<.<<<........>>>.>
>>......>>>>...<<.<<<..<<.<<<<<<....<<<<<<<<<....>
>>...<<<......>>>...>>>>>>....<<<<<.<<..<<<<..<<..
<<<..<<<<..<<<<<<......<<<<<<<<<<<.<<<<..<<<<<.<<<
<......>>>>.>>.>>>..>>>>...>.>>>>>>>>>>...>>>>>>>>
>>..>>>..<<<<........>>>>.....>>..>>>>.>>.....<<<<
<.....>>>>>.......>>>>>....>>>.>>>.....>>>>>>>....
.>.>>>>>...>>.>>>>.>>>.....<<<<<<........<.....<<<
.<<<<....>>>>.>>>....>.........>>>>>>.............
...<..........>...............>>>>>.....<<<<<<<<..
.....>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..
<<<<.<<....<<<<.<<<.<<<..<<<<..<.....<<<.<<<<<<<<<
<.<....>>>>>>>>>.>>..>>>.....>..>>>>..>>>.>>>.>>>>
...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>>>>>>>..
.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6w Structures of the human and Drosophila 80S ribosome.
Resolution6.0 Å
Binding residue
(original residue number in PDB)		R47 K70 R71 R74 T75 Q76 R80 I109 A112 K113 K116 R117 K120 K123
Binding residue
(residue number reindexed from 1)		R47 K70 R71 R74 T75 Q76 R80 I109 A112 K113 K116 R117 K120 K123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v6w, PDBe:4v6w, PDBj:4v6w
PDBsum4v6w
PubMed23636399
UniProtQ9VJY6|RL24_DROME Large ribosomal subunit protein eL24 (Gene Name=RpL24)

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