Structure of PDB 4v6w Chain CV Binding Site BS01

Receptor Information
>4v6w Chain CV (length=134) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGTAGGKFRISLGLPVGAVMNCADNTGAKNLYVIAVHGIRGRLNRLPAAG
VGDMFVATVKKGKPELRKKVMPAVVIRQRKPFRRRDGVFIYFEDNAGVIV
NNKGEMKGSAITGPVAKECADLWPRIASNASSIA
Ligand information
>4v6w Chain A5 (length=3806) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuauauacaaccucaacucauaugggacuacccccugaauuuaagcauau
uaauuaggggaggaaaagaaacuaacaaggauuuucuuaguagcggcgag
cgaaaagaaaacaguucagcacuaagucacuuugucuauauggcaaaugu
gagaugcaguguauggagcgucaauauucuaguaugagaaauuaacgauu
uaaguccuucuuaaaugaggccauuuacccauagagggugccaggcccgu
auaacguuaaugauuacuagaugauguuuccaaagagucguguugcuuga
uagugcagcacuaagugggugguaaacuccaucuaaaacuaaauauaacc
augagaccgauaguaaacaaguaccgugagggaaaguugaaaagaacucu
gaauagagaguuaaacaguacgugaaacugcuuagagguuaagcccgaug
aaccugaauauccguuauggaaaauucaucauuaaaauuguaauauuuaa
auaauauuaugagaauagugugcauuuuuuccauauaaggacauuguaau
cuauuagcauauaccaaauuuaucauaaaauauaacuuauaguuuauucc
aauuaaauugcuugcauuuuaacacagaauaaauguuauuaauuugauaa
agugcugauagauuuauaugauuacagugcguuaauuuuucggaauuaua
uaauggcauaauuaucauugauuuuuguguuuauuauaugcacuuguaug
auuaacaaugcgaaagauucaggauaccuucgggacccgucuugaaacac
ggaccaaggagucuaacauaugugcaaguuauugggauauaaaccuaaua
gcguaauuaacuugacuaauaaugggauuaguuuuuuagcuauuuauagc
uaauuaacacaaucccggggcguucuauauaguuauguauaauguauauu
uauauuauuuaugccucuaacuggaacguaccuugagcauauaugcugug
acccgaaagauggugaacuauacuugaucagguugaagucaggggaaacc
cugauggaagaccgaaacaguucugacgugcaaaucgauugucagaauug
aguauaggggcgaaagaccaaucgaaccaucuaguagcugguuccuuccg
aaguuucccucaggauagcuggugcauuuuaauauuauauaaaauaaucu
uaucugguaaagcgaaugauuagaggccuuagggucgaaacgaucuuaac
cuauucucaaacuuuaaauggguaagaaccuuaacuuucuugauaugaag
aucaagguuaugauauaaaugucccagugggccacuuuugguaagcagaa
cuggcgcugugggaugaaccaaacguaauguuacgugcccaaauuaacaa
cucaugcagauaccaugaaaggcguugguugcuuaaaacagcaggacggu
gaucauggaagucgaaauccgcuaaggaguguguaacaacucaccugccg
aagcaacuagcccuuaaaauggauggcgcuuaaguuguauaccuauacau
uaccgcuaaaguagaugauuuauauuacuugugauauaaauuuugaaacu
uuagugaguaggaagguacaaugguaugcguagaaguguuuggcguaagc
cugcauggagcugccauugguacagaucuugguggauaguagcaaauaau
cgaaugagagccuuggaggacugaaguggagaaggguuucgugugaacag
ugguugaucacgaguuagucgguccuaaguucaaggcgaaagcgaaaauu
uucaaguaaaacauaauuuugaacgaaagggaauacgguuccaauuccgu
aaccuguugaguauccguuuguuauuaaauaugggccucgugcucauccu
ggcaacaggaacgaccauaaagaagccgucgagagauaucggaagaguuu
ucuuuucuguuuuauagccguacuaccauggaagucuuucgcagagagau
augguagaugggcuagaagagcaugacauauacuguugugucgauauuuu
cuccucggaccuugaaaauuuaugguggggacacgcaaacuucucaacag
gccguaccaauauccgcagcuggucuccaaggugaagagucucuagucga
uagaauaauguagguaagggaagucggcaaauuagauccguaacuucggg
auaaggauuggcucugaagauugagauagucggccuugauugggaaacaa
uauuguggaacuuucuugcuaaaauuuuuaauuauuaauuauaacgauua
ucaauuaacaaucaauucagaacuggcacggacuuggggaauccgacugu
cuaauuaaaacaaagcauugugauggcccuagcggguguugacacaaugu
gauuucugcccagugcucugaaugucaaagugaagaaauucaaguaagcg
cgggucaacggcgggaguaacuaugacucucuuaagguagccaaaugccu
cgucaucuaauuagugacgcgcaugaauggauuaacgagauuccuacugu
cccuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggaaua
auuagcggggaaagaagacccuuuugagcuugacucuaaucuggcagugu
aaggagacauaagagguguagaauaagugggagauauuagaccucgguuu
gguaucgucaaugaaauaccacuacucuuauuguuuccuuacuuacuuga
uuaaauggaacguguaucauuuccuagccauuauacggauauauuuauua
uaucuuaugguauuggguuuugaugcaagcuucuugaucaaaguaucacg
aguuuguuauauaaucgcaaacaaauucuuuaauaaaacgaugcauuuau
guauuuuugauuugaaaauuugguauaacuccaauuacucagguaugauc
caauucaaggacauugccagguagggaguuugacuggggcgguacaucuc
ucaaauaauaacggaggugucccaaggccagcucagugcggacagaaacc
acacauagagcaaaagggcaaaugcugacuugaucucgguguucaguaca
cacagggacagcaaaagcucggccuaucgauccuuuugguuuaaagaguu
uuuaacaagaggugucagaaaaguuaccauagggauaacuggcuuguggc
ggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggcucu
uccuaucauugugaagcaaaauucaccaagcguuggauuguucacccaug
caagggaacgugagcuggguuuagaccgucgugagacagguuaguuuuac
ccuacuaaugacaaaacguuguugcgacagcauuccugcguaguacgaga
ggaacccgcagguacggaccaauggcacaauacuuguucgagcgaacagu
gguaugacgcuacguccguuggauuaugccugaacgccucuaaggucgua
uccgugcuggacugcaaugauaaauaaggggcaauuugcauuguauggcu
ucuaaaccauuuaaaguuuauaauuuacuuuauaaacgacaauggaugug
augccaauguaauuuguaacauaguaaauugggaggaucuucgaucaccu
gaugccgcgcuaguuacauauaaaagcauuauuuaauacaaugacaaagc
cuagaaucaauuguaaacgacuuuuguaacaggcaagguguuguaagugg
uugagcagcugccauacugcgauccacugaagcuuauccuuugcuugaug
auucga
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6w Structures of the human and Drosophila 80S ribosome.
Resolution6.0 Å
Binding residue
(original residue number in PDB)
G11 F14 R15 S17 G19 P21 A24 V25 I40 H43 R46 R48 L49 N50 R51 L52 K74 R85 K86 R89 F95
Binding residue
(residue number reindexed from 1)
G5 F8 R9 S11 G13 P15 A18 V19 I34 H37 R40 R42 L43 N44 R45 L46 K68 R79 K80 R83 F89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0017022 myosin binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v6w, PDBe:4v6w, PDBj:4v6w
PDBsum4v6w
PubMed23636399
UniProtP48159|RL23_DROME Large ribosomal subunit protein uL14 (Gene Name=RpL23)

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