Structure of PDB 6rxt Chain CU Binding Site BS01

Receptor Information
>6rxt Chain CU (length=176) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVQVVDYSNADGKMSKQELKVYLSSRPPDPTRKPEDSAELLANDLALQRL
IAESHILSEAGANPSHWQSSHAATTGTNTRAFATGRIAKKTTDMRIQALG
AKESILTQQKMPMNMRKGIVKHQEEKEKKRRQEARENGIVLEREVRPVDL
PAVGRMRGAELRISAKEAAAIAREVR
Ligand information
>6rxt Chain C1 (length=1152) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guuggggaagcccuagcggcugaaccucucggucgggccuccucuugggg
cgccuaggcggugucuucgggucgcgugcagccucccguccucgccugcc
gacagcgcucuggggaauucaggaggggaaagcagaugugccccgcggcg
agacuggcgcaccgccggacgagcugcuggggcacgcggguacgcuagcc
gcacgauaguuaccugguugauucugcuagucauaugcuugucucaaaua
cccaaucccgacacggggagguagugacaauaaauacugauacagggcuc
uuucgggucuuguaauuggaaugaguacaauuuaaaucccuuaacgagga
acaauuggagggcaagucuggugccagcagccgcgguaauuccagcucca
auagcguauauugcucguaguugaaccugauuaauagggacagucggggg
cgucaguauucaauugucagaggugaaauucuuggauuuauugaagacua
acaacugcgaaagcauucgccaaggauguuuucauuaaucaggaacguaa
acuauuagggaucggacggcguuuauuuuugacccguucggcaccuuacg
auaggaguauggucgcaaggcugaaaaauugacggaagggcaccaccagg
gguggagccugcgcgcgcgcuacacugacagagccagcgaguacucccuu
ggccgagaggcccggguaaacucugucgugcugaggaaucccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauagaggaaguaggucuccguaggugaaccugcgg
ag
<<<<<<.<.<<<<<<....>>>>>>.>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<..<<...<<<<.....>>>>...>>..>>>>>.>>>>>>>>.....<<<
<<<...<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>
....>>>>>>...........................<<<<.<<<<<<<.
.<.<<<<<.....>>>>>.>..>>>>>..>>>>>><<<<.<.....>.>>
>>...........................<<.<<<<<<...<.<<..<.<
<<...<<<<.....>>>.>>>>..>>...>.>....<<<<<<<<<<<<<<
....>>>>>>>>>.>>>>>.....<<..<...........>..>>.....
....<<<<<<.......<<<....>>>..................>>>>>
>..>>>>>>>>.<.<<...<<<.<<.....>>....<<<<<<.<<...<<
<<..<<<.<<<<<<.<...<<<......>>>......>.>>>>>>.>>>.
......<<....>>...>>>>..>>.>>>.>>>...>>>...>>.>....
.......<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>.....
..............................<<<<<<<<<<<<..<<.<<<
<<<..<<<.<<<..>>>.>>>.....<<<<<<<..............<<.
<<<<....>>>>.>>.....>>>>>>>..........>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>............
>>>>>..<<<<.<<......>>.>>>>...<<<<<<<<<....>>>>>>>
>>
Receptor-Ligand Complex Structure
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PDB6rxt Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution7.0 Å
Binding residue
(original residue number in PDB)		L116 K117 S151 A152 H185 T189 G190 T191 R194 R200 Q222 K224 P226 M227 M229 R230 K231 G232 I233 H236 R249 R257
Binding residue
(residue number reindexed from 1)		L19 K20 S37 A38 H71 T75 G76 T77 R80 R86 Q108 K110 P112 M113 M115 R116 K117 G118 I119 H122 R135 R143
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005730 nucleolus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxt, PDBe:6rxt, PDBj:6rxt
PDBsum6rxt
PubMed31378463
UniProtG0S5F1

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