Structure of PDB 8jiv Chain CT Binding Site BS01

Receptor Information

>8jiv Chain CT (length=159) Species: 4565 (Triticum aestivum)

PAGHGLRSRTRDLFARPFRKKGYIPLTTYLRTYKVGEHVDVKVNGAVHKG
MPHKFYHGRTGRVWNVTKRAIGVEINKQVGNRIIKKRIHVRVEHVQPSRC
NEEFLQRKLNNDKLKAEAKVRGEVISTKRQPAGPKPGFMVEGTTIETVTP
IPYDVVNDL

Ligand information

>8jiv Chain Aa (length=2863)

gcgaccccaggucaggcgggacuacccgcugaguuuaagcauauaaauaa
gcggaggagaagaaacuuacaaggauuccccuaguaacggcgagcgaacc
gggagcagcccagcuugagaaucgggcggcugugccguccgaauuguagu
cuggagaggcguccugcgacggaccgggcccaaguccccuggaaaggggc
gccugggagggugagagccccguccggcccggacccugucgcgaggcgcc
ucaacgagucggguuguuugggaaugcagcccaaaucgggcgguagacuc
cguccaaggcuaaauacaggcgagagaccgauagcgaacaaguaccgcga
gggaaagaugaaaaggacuuugaaaagagagucaaaagugcuugaaauug
ccgggagggaagcggaugggggccggcgaugcgccccggccguaugcgga
acggcugguccgccgcucggcucgggguguggacuguugucggccgcgcc
ggcggccaaagcccgggggcccuaggugcccccgguggccgucgucggca
cggccgcgcgccuaaaggcgugucccucggggcacugcgcugcaacggcc
ugcgggcuccccauccgacccgucuugaaacacggaccaaggagucugac
augcgugcgagucgacggguucugaaaccugggaugcgcaaggaagcuga
cgagcgggaggcccugggccgcaccgcuggccgacccugaucuucuguga
aggguucgaguuggagcacgccugucgggacccgaaagauggugaacuau
gccugagcggggcgaagccagaggcucugguggaggcucgaagcgauacu
gacgugcaaaucguucgucugacuuggguauaggggcgaaagacuaaucg
aaccaucuaguagcugguucccuccgaaguuucccucaggauagcuggag
cccaacgaguucuaucagguaaagccaaugauuagaggccuauucucaaa
cuuuaaauagguaggauggcgcggcugcuucggugagccgugccauggaa
ucgggcuccaagugggccauuuuugguaagcagaacuggcgaugcgggau
gaaccggaagccggguuacggugcccaacugcgcgcuaaccuagaaccca
caaaggguguuggucgaacuagccccgaaaauggauggcgcugaagcgcg
cgacccacacccggccaucugggcgagcgccaugccccgaugaguaggag
ggcgcggcggccgcugcaaaacccggggcgcgagcccgggcggagcggcc
gucggugcagaucuuggugguaguagcaaauauucaaaugagaacuuuga
aggccgaagaggagaaagguuccaugugaacggcacuugcacauggguaa
gccgauccuaagggacgggguaaccccggcagauagcgcacgcgccccga
aagggaaucggguuaagauuucccgagccgggauguggcgguugacggcg
acguuaggaaguccggagacgccggcgggggccucgggaagaguuaucuu
uucugcuuaacggccugccaacccuggaaacgguucagccggagguaggg
uccaguggccggaagagcaccggguguccggugcgcccccggcggcccau
gaaaauccggaggaccgccguucacgcccggucguacucauaaccgcauc
aggucuccaaggugaacagccucuggccaauggaacaauguaggcaaggg
aagucggcaaaacggauccguaacuucgggaaaaggauuggcucugagga
ccgacucagaacugguacggacaaggggaauccgacuguuuaauuaaaac
aaagcauugcgaugguccucgcggaugcugacgcaaugugauuucugccc
agugcucugaaugucaaagugaagaaauucaaccaagcgcggguaaacgg
caagguagccaaaugccucgucaucuaauuagugacgcgcaugaauggau
uaacgagauucccacugucccugucuacuauccagcgaaaccacagccaa
gggaacgggcuuggcggaaucagcggggaaagaagacccuguugagcuug
acucuaguccgacuuugugaauacuuauuccgugggucggaaguuuuggc
uccaaggccggccgauccgggcggaagacauugucagguggggaguuugg
cuggggcggcacaucuguuaaaagauaacgcagguguccuaagaugagcu
caacgagaacagaaaucucguguggaacaaaaggguaaaagcucguuuga
uucugauuuccaguacgaauacgaaccgugaaagcguggccuaucgaucc
uuuagcuucggaguuugaagcuagaggugucagaaaaguuaccacaggga
uaacuggcuuguggcagccaagcgauagcgacguugcuuuuugauccuuc
gaugucggcucuuccuaucauugugaagcagaauucaccaaguguuggau
uguucacccaccaauagggaacgugagcuggguuuagaccgucgugagac
agguuaguuuuacccuacugaugacagugucgcgauaguaauucaaccua
guacgagaggaaccguugauucacacaauuggucaucgcgcuugguugaa
aagccaguggcgcgaagcuaccgugugccggauuaugacugaacccucua
agucagaauccaagcuagcaugcgacgccucgacccacguuaggcccaag
ggcccgugggccgaagugcagcucccuucccgaauccuuugcagacgacu
uaagacggggcauuguaaguggcagagugacgauccacugagauccagcc
ccgucgcauucgu

........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<.......<.....>......
>>>>>..<<<....<......<<<<<<<<<...>>>>>>>>>......>.
.....<<<<<<<<.<<<<<<<<.<<<<<<<.....<<<<......>>>>.
((......<<<.....))>>>....>>>>>>>...>>>>>>>>.>>>>>>
>>........<<<<<<<........>>>>>>>.....<<<<<..((((((
>>>>>..>>>..................................<<....
>>...............<<<<....>>>>.....................
............<<<<<<<<<<<<......<.<<<<<<.<.......<<.
..<.>...>>........>..>.>>>>>.>.<.<<<<<<......<<...
.<..<......<..<<..<.......>.>>...>.....>..>....>>.
.......<<.<.<....>.>....<......>......>>..>>>>>>.>
....>>>.>>>>>>>>>..<<<<........>>>><<<<<<....<<<<<
<.<<<<<<..<<...<<<<<<....>>>>>>....>>...<<....>>..
..<<<<<..<<<<<.>>>>>...>>>>><<<<<<<<.....<....>...
..>>.>>>.>>>...>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<.>>>>>>>.....>>>...<<<<.<<.
<<........>>>>>>>>....>>>>>>>>>...<<.......>>.....
.>>>>>>...>..>.>>..<<<<<<....<.<<<....>>>.><<<<<<<
.<<..<<<.<<<<<<<.....<<<....<<<..<.<<..>>.>..>>>..
>>.>.....>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>
>>>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<...
...>>>...<<<<<<<...<<<(((.....<<<<<<.......<......
....<<<.<<<<<<...>>>>>>>>>..........))).>....>>>>>
>.>>>...>>>>>>><<<<.<<<<.........>>>>.>>>>....>>>>
>><.<<<<<<<<<<.......<<<.<<<<....>>>>>>>....>>>>>>
>>>>..>.....>>>>>><<.....<<.....<<<<<<.......>>>>>
><<<<<....<<<<<.<<...<<<<<....<<.....>>..>>>>>....
((<<<<<<...<<<...<<<....>>>........<<<..>>>..>>>..
..>>...<<<<<.........>>>>>))<<<<.<<<<<<<<...<<<...
.>>>...<...<<<<<<...<<<<.<<<<<<<.<<<<<.<<<<...[[..
>>>>.><...<<<<<.....<<<<<<....<<<<...>>>>....>>>>>
>.....>>>>>....><<<<<.>>>>>>>>>...>>>>>>>.>>>>....
.....>>>>>>...>..>>>>.>>>>>>>>>>>>..>>.....<<.....
.>>>>>>>.<<<<.....>>>>.>>>>>..<<<<.....<<<<<<<.<<.
........<.....<<<<<....<<..>>.....>>>>><<.<<<<<<..
....>>>>>>.>>............<<<<<<<<<..<<<.........>>
>..<<<<<<<....<<<<....>>>>......>>>>>>>...<<..<<<.
.<<<<<<....<<<.....<<<<....>>>>.....>>>.>>>>..>>>>
>......<...........<<<<<.......>>>>>.....>.....>>.
...>>.>>>>>>>..>..>>.>>>>>>>..>>>>>>....>>....<<<<
<........>>>>>....<<<<<..<<<.<<......<<<<.<<<<<<..
<<<<<.<<<.<<<...<<<..>>>...<<<<<.....<<<<.........
.....<<<..>>>..>>>>..>>>>>......>>>.>>>..>>>>>...<
<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...
<<<..<<<<.......>>>>..>>>.<<<....>>>.>>))).......<
<<<<<<<<<.))))))>>>>>>>>>>..........>>>>..>>>>>>..
.....<<.<.<.<<<<<<...<<....>>...>>>>>>...>>.>.>...
....<<<<<..<<<<<..<<<.<<<<<......>>>>>...>>>.<<<..
.......>>>.....>>>>>......>>>.>>....<<<<<<<....>>>
.>>>>....>>..>>>.>>>>>....<<<<<<<..<<<<...<<<<<...
..............>>>>>..<<<<<...<<<<....<<<<<<<<<.]].
..>>>>..>>>>>...>>>>..>>>>>..<<<...<<<<<..........
>>>>>...>>>..>>>>....>>>>>>>.....<<.......<..>....
>>.............................<<<<..<............
.>.<<<<<<<.<<<....<<<<.<..<<.>>..>>>>>...>>>....>>
>>>>>..>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8jiv Cryo-EM structure of wheat ribosome reveals unique features of the plant ribosomes.
• Resolution: 2.84 Å
• Binding residue (original residue number in PDB): P2 A3 G4 H5 G6 R8 S9 R10 R12 D13 L14 A16 R17 F19 K22 G23 Y24 K35 D41 K43 G46 A47 H49 K50 G51 H54 K55 Y57 H58 G59 R60 T61 T68 R70 N77 K78 V80 N82 R83 I85 K87 R88 I89 H90 R92 R100 C101 E104 F105 R108 K109 N112 K116 S127 K129 R130 Q131
• Binding residue (residue number reindexed from 1): P1 A2 G3 H4 G5 R7 S8 R9 R11 D12 L13 A15 R16 F18 K21 G22 Y23 K34 D40 K42 G45 A46 H48 K49 G50 H53 K54 Y56 H57 G58 R59 T60 T67 R69 N76 K77 V79 N81 R82 I84 K86 R87 I88 H89 R91 R99 C100 E103 F104 R107 K108 N111 K115 S126 K128 R129 Q130

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8jiv, PDBe:8jiv, PDBj:8jiv
• PDBsum: 8jiv
• PubMed: 38458197
• UniProt: F4YWL9