Structure of PDB 6hiv Chain CS Binding Site BS01

Receptor Information
>6hiv Chain CS (length=142) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKIAKSAFGFYLARRGQRKYPFLRRPHIKNTHSMNPSAPYFWSFMTAKSQ
MAFLPEENYITGDWTGKFFVSKRQVYTLQHATSGAKVRVKSFPSIFEFNS
PSRWNIGKEMNTLTKPRMDLIDEQMLTKKQRLDYVRAGLLPK
Ligand information
>6hiv Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
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....................<<<.......<<<<..............<.
..>..........................................<<...
.<<...<<<.......>>>..>>.......>>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
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PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)
K32 K35 A37 F38 F40 Y41 L42 A43 R44 R45 G46 Q47 K49 L53 R55 P56 H57 I58 K59 H62 Y70 M75 K78 F99 K102 R103 K120 F122 N141 P146 R147 K159 Q160 Y164
Binding residue
(residue number reindexed from 1)
K2 K5 A7 F8 F10 Y11 L12 A13 R14 R15 G16 Q17 K19 L23 R25 P26 H27 I28 K29 H32 Y40 M45 K48 F69 K72 R73 K90 F92 N111 P116 R117 K129 Q130 Y134
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ584T8

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