Structure of PDB 4v7e Chain CR Binding Site BS01

Receptor Information
>4v7e Chain CR (length=189) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVSLKLQKRLASSVLKCGKGKVWLDPNEVNEISMANSRQNIRKLVKDGFI
IRKPQKIHSRSRARRAHEAKQKGRHSGYGKRRGTREARLPTKILWMRRMR
VLRRLLRKYREAKKIDKHMYHDMYLKVKGNMFKNKRVLMESIHKSKAEKA
REKTLSDQFEAKRAKSKASRERKIARREERLAPGPERSC
Ligand information
>4v7e Chain Ad (length=1762) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugugcaaguaugaaccaauuugaacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguacgugcuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucugggaggggc
gcauuuauuagauaaaaggcugacgcgggcucugcucgcugauccgauga
uucaugauaacucgacggaucgcacggccuucgugccggcgacgcaucau
ucaaauuucugcccuaucaacuuucgaugguaggauaggggccuaccaug
guggugacgggugacggagaauuaggguucgauuccggagagggagccug
agaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaa
uccugacacggggagguagugacaauaaauaacaauaccgggcgcauuag
ugucugguaauuggaaugaguacaaucuaaaucccuuaacgaggauccau
uggagggcaagucuggugccagcagccgcgguaauuccagcuccaauagc
guauauuuaaguuguugcaguuaaaaagcucguaguuggaccuugggccg
gccggcaucgcgcuccuagccuuaauuggccgggucguguuuccggcauc
guuacuuugaagaaauuagagugcucaaagcaagccaucgcucuggauac
auuagcaugggauaacaucauaggauuccgguccuauuguguuggccuuc
gggaucggaguaaugauuaauagggacagucgggggcauucguauuucau
agucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaagc
auuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucgaa
gacgaucagauaccguccuagucucaaccauaaacgaugccgaccaggga
ucggcggauguugcuuauaggacuccgccggcaccuuaugagaaaucaaa
gucuuuggguuccggggggaguauggucgcaaggcugaaacuuaaaggaa
uugacggaagggcaccaccaggcguggagccugcgcuuaauuugacucaa
cacggggaaacuuaccagguccagacauagcaaggauugacagacugaga
gcucuuucuugauucuaugggugguggugcauggccguucuuaguuggug
gagcgauuugucugguuaauuccguuaacgaacgagaccucagccugcua
acuagcuaugcggagccaucccuccgcagcuagcuucuuagagggacuau
ggccguuuaggccacggaaguuugaggcaauaacaggucugucaugcccu
uagauguucugggccgcacgcgcgcuacacugauguauucaacgaguaua
uagccuuggccgacaggcccggguaaucuugggaaauuucaucgugaugg
ggauagaucauugcaauuguuggucuucaacgaggaaugccuaguaagcg
cgagucaucagcucgcguugacuacgucccugcccuuuguacacaccgcc
cgucgcuccuaccgauugaaugguccggugaaguguucggaucgcggcga
cgggggcgguucgccgcccccgacgucgcgagaaguccauugaaccuuau
cauuuagaggaagcagaagucguaacaagguuuccguaggugaaccugcg
gaaggaucauug
...<<<<....[[[[.>>>>.<<<.<<<<<<...<.<<..<......<<<
.<<<..<<...<<.....<<...........>>....>>>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>..........<<<............>>>.
<...<..<<<.....[[[.(((((<<<.........>>>...........
....>>>.>......>........<<<<......>>>.>.....>>>>>.
..>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>
>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<...
.......>>>.>>...<<....>>.....>>>>>>.........<<<...
.<<<.....>>>..>>>..>>...>.>.....<<.<<.<<..........
....>>.>>..>>......<<.................>>.........<
<<<<((....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>
>>>>>>>..........<.<{{.....<.<<...<<<.<.....<.<<<<
..>>>>.>...<..............<<<.....>>>............>
<<<<<<.<<.......<<...<.......>...<.......>.....>>.
.....>>.>>..>>>>.........<<<<<<<<<<.....))))).]]].
>>>>>>>>>>.......>....<<<<<<.<<...<<<<..<<..<<<<<<
<<...<<<......>>>......>>>>>>>>..>>.......<<....>>
...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...
<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..
<<<<<<<<.<<<........>>>>>>>>>>>..>>>...<<..}}>>...
>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..]]]].
.<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.......<<......
..>>..........<<<<<.<....<<<<<........<<.<<<......
..>>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<
<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<
<..<<......<<<<......>>>>........>>..>>>>.>>.....<
<<<<.....>>>>>........>>>>>....>>>.>>>.....>>>>>>>
.....>.>>>>>......>>>>.>>>.....<<<<.<.......<<....
...<<<.<<<<....>>>>.>>>....>>........>.>>>>.......
....<<<<<<..........>>>>>>..........>>>>>>....<<<<
<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..
<<.<..<.<<.<<....<<<<<<<..<<<..<<<<..<...<<...<<<.
<<<<<<<<<....>>>>>>>>>.>>>...>>...>..>>>>..>>>..>>
>>>>>...>>.>>.>...>.>>...>.....<<<<<<<<<....>>>>>>
>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v7e Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Resolution5.5 Å
Binding residue
(original residue number in PDB)
F159 K162 R163 R170 K173 R176 R177 R180
Binding residue
(residue number reindexed from 1)
F159 K162 R163 R170 K173 R176 R177 R180
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v7e, PDBe:4v7e, PDBj:4v7e
PDBsum4v7e
PubMed24499919
UniProtQ7XY20

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