Structure of PDB 8pv6 Chain CQ Binding Site BS01

Receptor Information
>8pv6 Chain CQ (length=183) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIENCFFCGRPAWPSKGITFMRNDGKAFRFCRSKCHKNFKMKRNPRKLK
WTKAYRKNAGKEMVVDSTLQFAARRNVPVRYNRELWQKTLKAMERISEIR
ARRERVFYKKRMAGKRAREVAAARKLVAENEHLLPRLRGSEKRRLAELAA
ERGVDVEELEREELAKLASKKKSKAFGGEVRRV
Ligand information
>8pv6 Chain C1 (length=3100) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agguugaccucggaucagguaggaggacccgcugaacuuaagcauaucaa
uaagcggaggaaaagaaaccaacagggauugcccuaguaacggcgaguga
agcggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuu
ggagaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacg
ccacagagggugagagccccguauaguuggaagccaagccuguguaaagc
uccuucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaa
auuucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguaga
gugaucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacguga
aauuguugaaagggaagcgcuugugaccagacuugcgcccggcggaucau
ccgguguucucaccggugcacuccgccgggcucaggccagcaucgguucu
ggcggggggauaaaggcccagggaauguggcuccuccgggaguguuauag
cccuggguguaauacccucgccgggaccgaggaccgcgcucugcaaggau
gcuggcguaauggucaccagcgacccgucuugaaacacggaccaaggagu
caagguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaag
ugaacguaggugagagcuucggcgcaucaucgaccgauccugauguauuc
ggauggauuugaguaggagcguuaagccuuggacccgaaagauggugaac
uaugcuuggauagggugaagccagaggaaacucugguggaggcucgcagc
gguucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagac
uaaucgaaccaucuaguagcugguuaccgccgaaguuuccggauagcagu
gucgaccuucaguuuuaugagagcgaaugauuagggacucgggggcgccu
ucauccauucucuguaagaagcccuuguuacuuaacugaacgugggcgaa
ugucgacacuagugggccauuuuugguaagcagaacuggcgaugcgggau
gaaccgaacgcgggguuaaggugccggaguggacgcucaucagacaccac
aaaaggcguuaguacaucuugacagcaggacgguggccauggaagucgga
auccgcuaaggacuguguaacaacucaccugccgaauguacuagcccuga
aaauggauggcgcucaagcgucccacccauaccccgcccucaggguagaa
acgaugcccugaggaguaggcggccguggaggucagugacgaagccuagg
gcgugagcccgggucgaacggccucuagugcagaucuuggugguaguagc
aaauacuucaaugagaacuugaaggaccgaaguggggaaagguuccaugu
gaacagcgguuggacauggguuagucgauccuaagccauagggaaguucc
guuucaaaggggcacucgugccccgggcgaaagggaagccgguuaauauu
ccggcaccuggauguggguuuugcgcggcaacgcaacugaacgcggagac
gacggcgggggccccgggcagaguucucuuuucuucuuaacggucuauca
cccuggaaacaguuugucuggagauaggguuuaauggccggaagagcccg
acacuucugucggguccggugcgcucucgacgucccuugaaaauccgcgg
gagggaauaauucucacgccaggucguacucauaaccgcagcaggucccc
aaggugaacagccucugguugauagaacaauguagauaagggaagucggc
aaaauagauccguaacuucgggaaaaggauuggcucuaaggguugggcac
gugcgugcgguuaacaaccaacuuagaacugguacggacagggggaaucu
gacugucuaauuaaaacauagcauugcgauggccagaaagugguguugac
gcaaugugauuucgcccagugcucuaugucaaagugaagaaauucaacca
agcgcggguaaacggcgggaguaacuaugacucucuuaagguuaacgaga
uucccacugucccuaucuacuaucuagcgaaaccacagccaagggaacgg
gcuuggcaaaaucagcggggaaagaagacccuguugagcuugacucuagu
uugacauugugaaaagacauaggagguguagaauaggugggagcuucggc
gccagugaaauaccacuacuccuauuguuuuuuuacuuauucaaugaagc
ggggcuggacuugcguccaacuucuggaguuaagguccuucgcgggccga
cccggguugaagacauugucagguggggaguuugggcacaucugcaggug
uccuaaggggggcucauggagaacagaaaucuccaguagaacaaaagggu
aaaaguccccuugauuuugauuuuugugaauacaaaccaugaaagugugg
ccccuuuagucccucgaaauuugaggcuagaggaaguuaccacagggaug
gcuuguggcggccaagcguucauagcgacgucgcuuugauccuucgaugu
cggcucuuccuaucauaccgaagcagaauucgguaagcguuggauuguac
ccacuaauagggaacgagcuggguuuagaccgucgugagacagguuaguu
uuacccuacugaugaacucgucgcaaugguaauucagcuuaguacgagag
gaaccgcugauucagauaauugguuuuugcgguuguccgaccgggcagug
ccgcgaagcuaccaucugcuggauaauggcugaacgccucuaagucagaa
uccaugccagaacgcgacgauacuacccgcacguuguagacguauaagaa
uaggcuccggccucguauccuagcaggcgauuccuccgccggccucgaag
uggccgucgguaauucgcguauugcaauuuagacacgcgcgggaucaaau
ccuuugcagacgacuuagaugugcgaaaggguccuguaagcaguagagua
gccuuguuguuacgaucugcugaggguaagcccuccuucgccuagauuuc
...........................<<<<<<.....<......>....
..>>>>>.>...<.....<<....>>..<<<<<......<<.....>>..
...>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>.
...<<<<<.<<<<<<<<<..<<<<<<..<<<...<<<<......>>>>.(
(......<<<.....))>>>.>..>>..>>>.>>>..>>>>....>>>>>
>>>.>>........<<<<<<<........>>>>>>>.....<<<<<..((
((((>>>>>..>>>....>.............................<<
....>>...............<<<<....>>>>.................
.................<<<<.<<<<<<.<...<<.<<<<<<<<<.....
<<<<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<
<<<<<<<<.......<<<<<<<<......<<<<<....>>>>>.......
>>>>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>
>>>>>>....>>>>>>>.>>>>..<<<<........>>>><<<<<<...<
<<<<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>...<<....>
>.......<<<<<..<<....>>...>>>>>.<<<<<<<<...<<....>
>...>>>>.>>.>>....>>>>.>>>>>>>>>.<<.<...<<<<<<....
.<<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<
<<.<<.<<........>>>>>>>>....>>>>>>>>>...<<.......>
>......>>>>>>......>.>>...<<<<<......<<..>>..<<<<<
<<<<.....<<.<<<<<<<.........<<....<<<...<<<<<..>>>
>>.>>>..>>..>>>>>...<<<<.<<<<.<......>>>>>.>>>>.>>
>>.>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<...
...>>>...<<<<<<<...<<<(((.....<<<<<<.....<<.......
...<<<.<<<<<<<<<<.......<<<<<.<<<...<<.........>>.
..>>>.........<<......>>...>>>>>...>>>>>>>>>>>>>..
........))).>>...>>>>>>.>>>...>>>>>>><<<<<<<<<....
.....>>>>>>>>>....>>>>>.<.<<<<<<<<.<<......<<<<.<<
<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<
.....<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<
...<<.....>>.>>>>>>....((<<<<<<...<<<...<<<....>>>
........<<<<<......>>>>>.>>>....>>...<<<<<........
>>>>>))<<<<.<<<<.<<<....<<<....>>>...<..{<<<<<<...
<<<<.<<<<<<<.<<<<<.<<<<...[[..>>>>.><...<<<<<....<
<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<<<<
<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>.
..>.....>>>...>>>>>>>>>>>>..>>.....<<......>>>>>>>
.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<.........
<.....<<<<<....<....>.....>>>>><<.<<<<<<<<<<<.<<<<
<..>>>>>......>>>>>..>>>>>>.>>............<<<<<<<<
<..<<<.........>>>..<<<<<<<....<<<<.....>>>>......
>>>>>>>......<<<..<<<<<<..<<<.....<<<<....>>>>....
.>>>.>>>>..>>>>><<<<<<.......>>>>>>..........>>.>>
>>>>>..>..>>.>>>>>>>..>>>>>>....>>....<<<<<.......
.>>>>>....<<<<<..<<<........<<<<<.<<<<<<..<<<<<.<<
<<<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....>>
............>>>>>.>>>>>>>.>>>>>>>>>>...<<<<<.....<
<<<..<<<<<....>>>>>..........}...<<<<<.....>>>>>..
>>>>..>>>>>.....>>>>>>>>..>>>>>...<<.<<<<<<..>>>>>
>>>...<<<<<<<...<<<<<<.......>>>>>>.....<<....((>>
....>>>>>>>...<<<.<<<<<....>>>>.>>>>.<<<....>>>...
))<<<<<<<..<<<<.))))))>>>>>>>>>>>.>>>>..>>>>>>>...
......<<<<<<...<<.......>>...>>>>>>...............
<<<<...<<<<..<.<<<<<<<......>>>>>>>...>.<<<.<...>.
>>>.....>>>>.....>>>>......<<<<<<<....>>>.>>>>....
....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<............
.....>>>>>.><<<<<...<<<<....<<<<<<<<<<]]..>>>>>..>
>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>>>>...
>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<......<<.....
..<<<....>>>....>>........<<<<.....<<<.<<<<<......
.>>>>>.>>>....>>>>..............>>>>>.>>>>>...<<<<
<<<.............>>....<<<<<<<<<.<<<....<<<<....<<<
<<......>>>>>...>>>>...>>>....>>>>..>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv6 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.94 Å
Binding residue
(original residue number in PDB)
S16 G18 S34 K35 K38 M42 R44 K50 W51 K53 R56 K61 R111 M112 K115 R118 R182 V183
Binding residue
(residue number reindexed from 1)
S16 G18 S34 K35 K38 M42 R44 K50 W51 K53 R56 K61 R111 M112 K115 R118 R182 V183
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005730 nucleolus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8pv6, PDBe:8pv6, PDBj:8pv6
PDBsum8pv6
PubMed37921038
UniProtG0S497

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