Structure of PDB 8oeq Chain CQ Binding Site BS01

Receptor Information
>8oeq Chain CQ (length=223) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AILSKKKKLVADGVFYAELNEFFTRELAEQGYAGVEVRKTPSKLEVIVKA
SNTQGVLGEQGRRIHELTSLIVKRFKLSPEGIAIYAERVEERGLSAAVQA
EALKAKLLSGLPIRRAAYGVLRFAMGAGAKGVEVVISGKLRAARAKSQKY
ADGFMIHSGQPTRDFIDIAIRHVLMRQGVLGIKVKIMKDPAANRFGPRAL
PDAVKIAEAKDEDEVIPAPTVKS
Ligand information
>8oeq Chain CM (length=1726) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaauaac
uuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucugc
ccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgggu
aacggggaauaaggguucgauuccggagagggagccugagaaacggcuac
cacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauaacgauacaggguuguaauuggaaugaguaca
auguaaauaccuuaacgaggaacaauuggagggcaagucuggugccagca
gccgcgguaauuccagcuccaaaagcguauauuaaaguuguugcaguuaa
aaagcucguaguugaaccuugggcuuggcuggccgguccuggacccagcc
gagccuuuccuucuggguagccauuuauggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggccuuugcucgaauauauuagcaug
gaauaauagaauaggacguuaugguucuauuuuguugguuucuaggacca
ucguaaugauuaauagggacggucggggguaucaguauucaguugucaga
ggugaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuacc
aaggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauc
agauaccgucguagucuuaaccauaaacuaugccgacuagggaucgguug
uuguucuuuuauugacgcaaucggcaccuuacgagaaaucaaagucuuug
gguucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
gaaacucaccagguccagacacaauaaggauugacagauugagagcucuu
ucuugauuuugugggugguggugcauggccguucuuaguugguggaguga
uuugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauagu
gcugcuagcauuugcugguauagucacuucuuagagggacuaucgauuuc
aagucgauggaaguuugaggcaauaacaggucugugaugcccuuagacgu
ucugggccgcacgcgcgcuacacugacggagccagcgaguagccuuggcc
gagaggucugggaaaucuugugaaacuccgucgugcuggggauagagcau
uguaauuguugcucuucaacgaggaauuccuaguaagcgcaagucaucag
cuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuacua
ccgauugaauggcuuagugaggccuccggauugguuuagggaaccgagaa
gcuggucaaacuuggucauuuagaggaaguaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<.........((((.<<<....>>>..............>>>>>>.
....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.
<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>>>>
..>>>..>....>.>.....<<<<...<...>...>>>>......<<..<
...........>..>>.........<<<<<((......<<<<.....<<.
.))>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<[[..
...<.<<...<<<.<<....<<<<<<<<<<<<............>>>>>>
>>>>>>......<<......................>>.....<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........<<<..<<<<<<<<<.....))))....>>>>>>>>
>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<
<......>>>......>.>>>>>>..>>.......<<....>>...>>>>
...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<.
....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<
<..<<........>>.>>>>>>>>..>>>...<<..]]>>...>>.....
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}<<<<<.
<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<....<<<<<........<<.<<<........>>>.
>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.<<<<<....
>>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<
<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....<<<<<<...
..>>>>>>.......>>>>>.....>>.>>>.....>>>>>>>.....>.
>>>>>...>>.>>>>.>>>.....<<<<<<<......<<...<<<.<<<<
....>>>>.>>>....>>.......>>>>>>>...........<<<<<<.
.........>>>>>>..........>>>>>>....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<..<...<<<<<.......>>>>>...
>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<
<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
I5 K8 K9 K10 R28 K142 R144 A146 R147 A148 K152 F157 I159 H160 S161 G162 Q163 H175 R179 Q180 G181 V182 G184 K186 P204 D205
Binding residue
(residue number reindexed from 1)
I2 K5 K6 K7 R25 K139 R141 A143 R144 A145 K149 F154 I156 H157 S158 G159 Q160 H172 R176 Q177 G178 V179 G181 K183 P201 D202
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