Structure of PDB 7pua Chain CQ Binding Site BS01

Receptor Information
>7pua Chain CQ (length=247) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PWWNFQTEHRQRCVLMYGGARTKNTHNANHRVFIKKYKRNAFPNRTRHHW
AVSMTGVLSQRPRRMPWPYDLTSLIFNQPRQGSDKIGYVVGTSMLKTAVV
ATNHMVYYPKFNQRVSRTKRFFAHDEDLACVEGDLVHIKQCRKISKYKHY
YVFSILEPNVEGRERLKLGLKAVPPPLFGYPVSRRIVKLNLTSTEGTQEK
LAAAIQEHVQDAYRFSGPTPDQPRNRLADPVTFEDANNMIAPNAPAA
Ligand information
>7pua Chain CA (length=501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaaauaaauuaaauuagu
cagaaauggaugccagccguugcgguaauuucuaugcuuuuaaauauuau
acaaaauuguuaagugcugauuuaaccaauaaaaauauaaauaauuuuac
cauuagguauuuuauucauauaauuaauaggauaauauuuguaguuuuug
auaccaugauaaggauuauaaauugaaaguguuaauaucauaaucaaaau
uuauuauuuauauuaaauauguauguguagauaaaauaagacccaccaau
uuuuauaauaaaaauaacgugcaguaauuaauauauuuauaaaaauauau
u
..............................<<<<<....<........<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
.......................................>.......<<<
.....<<<<<.....<<....>>.......>>>>>>>>.....>.>>>>.
.....<<<<<<<<<<....>>>>>>.>>>>..................<<
<....>>>..<<<<<...................................
......<.<<<<...................>>.>>>.............
..............................>>>>>........<<<..<<
<<<<.....>>>>>>...>>>........<<<<<<<<<....>>>>>>>>
>
Receptor-Ligand Complex Structure
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PDB7pua Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		F14 Q15 H18 R30 N33 T34 H35 N36 A37 H39 R40 K47 R48 N49 F51 P52 N53 T55 R56 H57 H58 W59 A60 S62 M63 T64 V66 L67 Q69 R70 R72 R73 P75 R89 Q90 S102 M103 L104 K105 T106 H113 P118 K119 Q122 R123 R126 K128 R129 Q149 K152 S154 K155 Y156 K157 H158 Y189 P190 V191 S192 R193 P227 P229 D230 R233
Binding residue
(residue number reindexed from 1)		F5 Q6 H9 R21 N24 T25 H26 N27 A28 H30 R31 K38 R39 N40 F42 P43 N44 T46 R47 H48 H49 W50 A51 S53 M54 T55 V57 L58 Q60 R61 R63 R64 P66 R80 Q81 S93 M94 L95 K96 T97 H104 P109 K110 Q113 R114 R117 K119 R120 Q140 K143 S145 K146 Y147 K148 H149 Y180 P181 V182 S183 R184 P218 P220 D221 R224
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pua, PDBe:7pua, PDBj:7pua
PDBsum7pua
PubMed35042777
UniProtC9ZYU9

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