Structure of PDB 7zrz Chain CP1 Binding Site BS01

Receptor Information
>7zrz Chain CP1 (length=220) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQKLPQRSHGPKDFLPDGSAAQAERLRRCREELWQLLAEQRVERLGSLVA
AEWRPEEGFVELKSPAGKFWQTMGFSEQGRQRLHPEEALYLLECGSIHLF
HQDLPLSIQEAYQLLLTDHTVTFLQYQVFSHLKRLGYVVRRFQPSLEIIF
DVYQADAVATFRKNNPGKPYARMCISGFDEPVPDLCSLKRLSYQSGDVPL
IFALVDHGDISFYSFRDFTL
Ligand information
>7zrz Chain ZN1 (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcucuguggcgcaauggauagcgcauuggacuucuagagaaauucaaag
guuguggguucgagucccaccagaguc
<<<<<<<..<<<<........>>>>.<<<<.<<<...>>>....>>>>..
...<<<<<.......>>>>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7zrz Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		Q31 Q35 R36 R73 F461 R462 N464
Binding residue
(residue number reindexed from 1)		Q2 Q6 R7 R44 F161 R162 N164
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7zrz, PDBe:7zrz, PDBj:7zrz
PDBsum7zrz
PubMed37231152
UniProtQ7Z6J9|SEN54_HUMAN tRNA-splicing endonuclease subunit Sen54 (Gene Name=TSEN54)

[Back to BioLiP]