Structure of PDB 6zqc Chain CL Binding Site BS01

Receptor Information
>6zqc Chain CL (length=781) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGKMARTMQRSSDVNERKLHVPMVDRTPEDDPPPFIVAVVGPPGTGKTTL
IRSLVRRMTKSTLNDIQGPITVVSGKHRRLTFLECPADDLNAMIDIAKIA
DLVLLLIDGNFGFEMETMEFLNIAQHHGMPRVLGVATHLDLFKSQSTLRA
SKKRLKHRFWTEVYQGAKLFYLSGVINGRYPDREILNLSRFISVMKFRPL
KWRNEHPYMLADRFTDLTHPELIETQGLQIDRKVAIYGYLHGTPLPSAPG
TRVHIAGVGDFSVAQIEKLPDPCPTPFYQQKLDDFERLIYAPMSDVGGVL
MDKDAVYIDIGNIGKLIYMDNISPEECIRRWRGVDLEKFVPYFDTFEKLA
KKWKSVDAIKERFLDTWYELQKAKISKQLEINNIEYQEMTPEQRQRIEGF
KAGSYVRIVFEKVPMEFVKNFNPKFPIVMGGLLPTEIKFGIVKARLRRHR
WHKKILKTNDPLVLSLGWRRFQTLPIYTTTDSRTRTRMLKYTPEHTYCNA
AFYGPLCSPNTPFCGVQIVANSDTGNGFRIAATGIVEEIDVNIEIVKKLK
LVGFPYKIFKNTAFIKDMFSSAMEVARFEGAQIKTVSGIRGEIKRALSKP
EGHYRAAFEDKILMSDIVILRSWYPVRVKKFYNPVTSLLLKEKTEWKGLR
LTGQIRAAMNLETPSNPDSAYHKIERVERHFNGLKVPKAVQKELPFKSQI
HQMKPQKKKTYMAKRAVVLGGDEKKARSFIQKVLTISKAKDSKRKEQKAS
QRKERLKKLAKMEEEKSQRDKEKKKEYFAQN
Ligand information
>6zqc Chain D2 (length=446) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaug
.<<<....>>>...<<<<<<<<<..>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<...<<<<<..<<<<<<<<<<.<<
<<<<<<....>>>>>>>>.>>>>>>>>>>.>>>>>..>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<..<
<<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>
>.....<<<<<<...<<<<<<<<<<<<<<<<........>>>>>>>.>.>
>>>>>>>....>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqc 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		S1081 H1084 Q1085 M1086 K1087 P1088 Q1089 K1090 K1091 T1093 Y1094 K1107 R1110 Q1114 L1117 T1118 K1121
Binding residue
(residue number reindexed from 1)		S698 H701 Q702 M703 K704 P705 Q706 K707 K708 T710 Y711 K724 R727 Q731 L734 T735 K738
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:2000232 regulation of rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0032040 small-subunit processome

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqc, PDBe:6zqc, PDBj:6zqc
PDBsum6zqc
PubMed32943521
UniProtQ08965|BMS1_YEAST Ribosome biogenesis protein BMS1 (Gene Name=BMS1)

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