Structure of PDB 6zqe Chain CK Binding Site BS01

Receptor Information
>6zqe Chain CK (length=222) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNLSSFEKQQIEIRKQIEQLENEAVAEKKWSLKGEVKAKDRPEDALLTEE
LEFDRTAKPVPVITSEVTESLEDMIRRRIQDSNFDDLQRRTLFELSDVKS
SKSLAEIYEDDYTALSEELQKAHSEISELYANLVYKLDVLSSVHFVPKPA
STETPTISMEDAQPLYMSNASSLAPQEIYNVGKAEKDGEIRLKNGVAMSK
EELTREDKNRLRRALKRKRSKA
Ligand information
>6zqe Chain D3 (length=1447) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucugguugauccugccaguagucauaugcuugucucaaagauuaagccau
gcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucauu
aaaucaguuaucguuuauuugauagucaugguauaacugugguaauucua
gagcuaauacaugcuaucucgacccuuuggaagagauguauuuauuagau
aaaaaaucaaugucuucggacucuuugaugauucauaauaacuuuucgaa
ucgcauggccuugugcuggcgaugguucauucaaauuucugcccuaucaa
cuuucgaugguaggauaguggccuaccaugguuucaacggguaacgggga
auaaggguucgauuccggagagggagccugagaaacggcuaccacaucca
aggaaggcagcaggcgcgcaaauuacccaauccuaauucagggagguagu
gacaauaaauaacgauacagggcccauucgggucuuguaauuggaaugag
uacaauguaaauaccuuaacgaggaacaauuggagggcaagucuggugcc
agcagccgcgguaauuccagcuccaauagcguauauuguuguugcaguua
aaaagcucguaguugaacuuugggcccgguuggccggucggauuuccaac
ggggccuuuccuucuggcuaaccuugaguccuuguggcucuuggcgaacc
aggacuuuuacuuugaaaaaauuagaguguucaaagcaggcguauugcuc
gaauauauuagcauggaauaauagaauaggacguuugguucuauuuuguu
gguuucuaggaccaucguaaugauuaauagggacggucgggggcaucagu
auucaauugucagaggugaaauucuuggauuuauugaagacuaacuacug
cgaaagcauuugccaaggacguuuucauuaaucaagaacgaaaguuaggg
gaucgaagaugaucagauaccgucguagucuuaaccauaaacuaugccga
cuagggaucgggugguguuuuuuuaaugacccacucggcaccuuacgaga
aaucaaagucuuuggguucugggggaguauggucgcaaggcuaaaaaagg
aauugacggaagggcaccaccaggaguggagccugcggcgcgcuacacug
acggagccagcgagaccuuggccgagaggucuugggaaacuccgucgugc
uggggauagagcauuguaauuauugcucuucaacgaggaauuccuaguaa
gcgcaagucaucagcuugcguugauuacgucccugcccuuuguacacacc
gcccgucgcuaguaccgauugaauggcuuagugaggccucaggaucugcu
uagagaagggggcaacuccaucucagagcggagauuuggacaaacuuggu
cauuuaggaacuaauuccguaggugaaccugcggaaggaucauuaaa
.<<<<<.......>>>>>.....((((((................[[[.[
[[..<<....<<....<<..........>>...>>.>>......{{....
....[[[..{{..{{....[[[........<<....<<.<<<.....>>>
.>>.....>>.....<<<<<..<<....>>..>>>>>[...((((((...
...<<<<<<<.<<<....>>>....<<......>>)))))).....]...
<<<<..<<<.....>>>.>>>>....]]]...}}}}..]]].<<<....<
<<....<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<
<<....>>>>....>>>.}}.<<.<<<..........>>>.>>.<.<<..
..>>.>...]]]]]].........<<<....<<<.....>>>..>>>...
............<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<
<..<...........>..>>.........<<<<<<.......<<<....>
>>..................>>>>>>..))))))..........[[[<<.
......{{...[[[.[[....<<<<<<.<<<<<............>>>>>
.>>>>>>....<<<<<<........<<<<.......>>>>........>>
>>>>...<<<<<.<<.......<<...<.......>..<<<.....>>>.
...>>......>>.>>..>>>.........[[...[.(((((......>>
>>>>>..))))).]..]].....]]....<<<<<<.<<...<<<<..<<.
.<<<<<<.<...<<<......>>>......>.>>>>>>..>>.......<
<....>>...>>>>..>>.>>>.>>>...]]]...}}......<<<<<<<
...<...<<<...........>>>...>>>>>>>>..........<<<.<
<.<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>...<<..
>>>>...>>.....>>>.]]].............................
....<<<<<<<<<<<<..<<.<<<<<...<<<.<<<.>>>.>>>.....<
<<<<<<.........<<..<<<<....>>>>..>>....>>>>>>>....
.......<<<<<<..........>>>>>>...........>>>>>....<
<<<<<<<.......>>>>>>>>......>>...>>>>>>>..........
..>>>>>..<<<<.<<....<<<<<<<<.<<<..<.<<..<...<<<<<<
<.<<<<.<<<......>>>.>>>>.>>>>>>>..>..>>.>..>>>.>>>
>>>>>.>>.>>>>.<<<<<<<<<....>>>>>>>>>...........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqe 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution7.1 Å
Binding residue
(original residue number in PDB)		K327 A491 N511 R527
Binding residue
(residue number reindexed from 1)		K33 A174 N194 R210
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034457 Mpp10 complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqe, PDBe:6zqe, PDBj:6zqe
PDBsum6zqe
PubMed32943521
UniProtP47083|MPP10_YEAST U3 small nucleolar RNA-associated protein MPP10 (Gene Name=MPP10)

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