Structure of PDB 4v8i Chain CK Binding Site BS01

Receptor Information
>4v8i Chain CK (length=114) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQ
LAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDT
PVPHNGCRPKKKFR
Ligand information
>4v8i Chain CA (length=1491) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaaga
caugcaagucgugcgggccgcguggucagcggcggacgggugaguaacgc
gugggugaccuacccggaagagggggacaacccggggaaacucgggcuaa
ucccccauguggacccgccccuugggguguguccaaagggcuuugcccgc
uuccggaugggcccgcgucccaucagcuaguuggugggguaauggcccac
caaggcgacgacggguagccggucugagaggauggccggccacaggggca
cugagacacgggccccacuccuacgggaggcagcaguuaggaaucuuccg
caaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcccuu
cgggguguaaacuccugaacccgggacgaaacccccgacgaggggacuga
cgguaccgggguaauagcgccggccaacuccgugccagcagccgcgguaa
uacggagggcgcgagcguuacccggauucacugggcguaaagggcgugua
ggcggccuggggcgucccaugugaaagaccacggcucaaccgugggggag
cgugggauacgcucaggcuagacggugggagagggugguggaauucccgg
aguagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggca
gccaccugguccacccgugacgcugaggcgcgaaagcguggggagcaaac
cggauuagauacccggguaguccacgcccuaaacgaugcgcgcuaggucu
cugggucuccugggggccgaagcuaacgcguuaagcgcgccgccugggga
guacggccgcaaggcugaaacucaaaggaauugacgggggcccgcacaag
cgguggagcaugugguuuaauucgaagcaacgcgaagaaccuuaccaggc
cuugacaugcuagggaacccgggugaaagccuggggugccccgcgagggg
agcccuagcacaggugcugcauggccgucgucagcucgugccgugaggug
uuggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcgg
uucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggagg
ggacgacgucuggucagcauggcccuuacggccugggcgacacacgugcu
acaaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgca
aaaaggugggcccaguucggauuggggucugcaacccgaccccaugaagc
cggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguuccc
gggccuuguacacaccgcccgucacgccaugggagcgggcucuacccgaa
gucgccgggagccuacgggcaggcgccgaggguagggcccgugacugggg
cgaagucguaacaagguagcuguaccggaaggugcggcugg
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<
<.<<<..<<<..<<.<<<<<..>>>>>.>>>>>......<<.......<<
<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>....
.>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<...>>>>.>
>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.......>>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<<..>>>>>...>>>>>>>........<<<
....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<..
..>>>>.....>>>>....<<<<<......<.<<<<.....>>>>..>..
.....>>>>>......<<<<<(((...<<<<<.....<<.)))>>.....
..>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<...
<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....>
>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<
.<..<<<......>>>.....>.>>>>>>>...........<<....>>.
>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<...<
<<<.........>>>>...>>>>>>>>..........<<<<<<..<<<<<
<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<..
....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<
<<<<..<<<<<<<<<<......<<........>>..........<<<<<<
<......<<<<<<<<..<<<<<<<....>>>>>>>...<<<......>>>
..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>.
.<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<...<<<
.....>>>>.....>>>>>>>.....<<<<<....>>>>>........>>
>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>
.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>.
....>>>>>>>...........<<<<<<<........>>>>>>>......
....>>>>>>....<<<<<<<..........>>>>>>>......>>...>
>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<...
<.<<<<.....<<....>>..>>>>.>..>>>>>>>>>>>>>..>>>.>>
>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v8i How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y20 H22 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 G52 S53 K55 R85 V114 H116 N117 G118 C119 R120 K122 K123
Binding residue
(residue number reindexed from 1)		Y8 H10 N14 N15 I17 T19 G25 N26 P27 W30 S32 G34 G40 S41 K43 R73 V102 H104 N105 G106 C107 R108 K110 K111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v8i, PDBe:4v8i, PDBj:4v8i
PDBsum4v8i
PubMed22605777
UniProtP80376|RS11_THET8 Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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