Structure of PDB 8i9t Chain CJ Binding Site BS01

Receptor Information
>8i9t Chain CJ (length=380) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKAKKKGKSGAARNYMTRTQAVKKLQLSLPDFRKLCIWKGIYPREPRDRR
KVNKSATASTTFYYTKDIQYLLHEPLLQKFREQKALEKKISRALGRGDVS
NAARLERNANLPEKTGKPRYTLNHIIRERYPTFQDALRDLDDCLSMLFLF
ANLPSTTAVPAKMIARCERLCHEFQHYLIVTHSLRKSFLSIKGIYYQANI
QGEDILWLVPYKFNQRIVGDVDFRIMGTFVEFYMTLLGFVNYRLYTSIGL
KYPPKFDQVKDDQGAELAAFSLEGLNDPSQLFANFTFFLSRETPRQPLEF
ILRAFGCKRIGWDAVLGEGAFTTDESDPRITHQIIDRPGRYPGRIYVQPQ
WVWDSINDEELKPPELYAPGAQLPPHLSPF
Ligand information
>8i9t Chain C2 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauaaguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgcccgccgguauuccggcgggcaugccuguucgag
cgucauuu
.........................................<<<<<<.<<
.....>>>.....(.<<<(.....>>............).>>>..)...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i9t Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		K5 S10 G11 R14 N15 Y16 K25 Q70
Binding residue
(residue number reindexed from 1)		K4 S9 G10 R13 N14 Y15 K24 Q69
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i9t, PDBe:8i9t, PDBj:8i9t
PDBsum8i9t
PubMed37129998
UniProtG0SHX6

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