Structure of PDB 6hiv Chain CJ Binding Site BS01

Receptor Information
>6hiv Chain CJ (length=800) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YYWSRYRMPTQMPKFDGPAPVAAPQSMNSTKTNEFIDPIDDKFPMSIRGP
LVRPDVPEDQYVDSWYICTSMTHHMGDYRPWSASAPPNAFRFRPFNEFDA
KGREYVQYMREFARFDPRKSRGNGQKGFPFRDAYLTKMNEANQKTPPPTL
ETIMDRAVREHHQHARILSPLEVQRDVGRLEPIPSYAGKINADRSVFPFQ
WKTEDWYEYEVAKVRNRRFVFENTEEDGIRGSEVTYKIVLEGFWDHHVMK
LAEDVCMFLKDVGRQIVEEKLVAVRRLLQGGAVDPELLAAFNCARAGPFG
GLDEYDKEEVANFLRSDLRRLEEQCLSVINRCNVPVPGATNIYDPHTSWP
HVEKLEPWVRMAEFWTSSSDTSFTELEMSTAHYEFRKFFRVIICKLPFQS
TEFEKRMYDIRHWLHRQTSCEFHTIYRRNVIHDSAVFPTEHDPATPTTHE
HHRMFSFALDWQSAPVNRLSTDTVHEGESWDAVAQRLGCSVGELKDANAE
RETIEAGVVINVPVTATRRLTSFGATPLVLPLKTTSAKDGERIRTWEEAA
AILDCTVEELQQCNGHAALTYQKKESETELVAPLSCWTSTSESEFSPVER
VHANDTLVAIARRLQCSEEALRAVNDGITDVSGLDFVRVPPEARRPRRLV
EPQLRPQAATDALLARTIAEEETFKLKSIPHLPQNAERFPHEYHTPTSRF
PPTPSETPATQDWMAYTAKYLDKQFTISAEPAPVYNVNKLWPMQQIPGKV
DQTPFEEDQTWLLHSIPVQQLEMHHHEKDLQDLPFINHEQFPRSLEWNAP
Ligand information
>6hiv Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaaguguug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
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....................<<<.......<<<<..............<.
..>..........................................<<...
.<<...<<<.......>>>..>>.......>>........<<....>>..
..................................................
.................<<<.(...<<<<<.....<<..).>>.......
>>>>>>>>.......>>>>............<..................
.<.......>.....................>............<<<...
.>>>................<......>..>>>..<<.............
.<<<<<............................................
..................................................
.....................>>>>>..................>>....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)		S38 M54 P59 L60 S376 S377 S378 T380 F382 T383 E384 M387 S388 H711 P713 S715 L779 Q787 L788
Binding residue
(residue number reindexed from 1)		S29 M45 P50 L51 S367 S368 S369 T371 F373 T374 E375 M378 S379 H694 P696 S698 L762 Q770 L771
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ57Z45

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