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Receptor Information

>8pv7 Chain CI (length=152) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQPGVMYIARLPHGFYEHELRGYFSQFGEITRLRVVRNKKTGASRHRAFI
EFADAEVADIAARTMDKYLLFGHILTCKIVPPAQVHPDLFKGANRRFKVV
PWNKMAGRQLERPLSESQWQVKVAKEEQRRAARAEKLKEMGYEFEAPALK
VP

>8pv7 Chain C3 (length=82) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

uucaaccaucaagcccugggcuuguguuggggacccgcggcugcucgcgg
gcccugaaaagcaguggcgggcgugccagccg

.........<<<<<<...>>>>>>....<<<<.<<<<<<<....>>>>>>
>>>>>.........<<<<<<<..>.>>.>>>>

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8pv7 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution	2.12 Å
Binding residue (original residue number in PDB)	Y190 R193 H201 R217 V218 V219 R220 N221 K222 K223 S227 R228 H229 R230 F254 H256 H269 L272 K274 G275 A276 R278 R279 F280 K281 V283 P284 W285 N286 R291 K305 R312 R316
Binding residue (residue number reindexed from 1)	Y7 R10 H18 R34 V35 V36 R37 N38 K39 K40 S44 R45 H46 R47 F71 H73 H86 L89 K91 G92 A93 R95 R96 F97 K98 V100 P101 W102 N103 R108 K122 R129 R133

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

	Cellular Component
GO:0005730	nucleolus

PDB	RCSB:8pv7, PDBe:8pv7, PDBj:8pv7
PDBsum	8pv7
PubMed	37921038
UniProt	G0S1H0

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Structure of PDB 8pv7 Chain CI Binding Site BS01