Structure of PDB 8i9y Chain CI Binding Site BS01

Receptor Information
>8i9y Chain CI (length=146) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQPGVMYIARLPHGFYEHELRGYFSQFGEITRLRVVRNKKTGASRHRAFI
EFADAEVADIAARTMDKYLLFGHILTCKIVPPAQVHPDLFKGANRRFKVV
PWNKMAGRQLERPLSESQWQVKVAKEEQRRAARAEKLKEMGYEFEA
Ligand information
>8i9y Chain C2 (length=256) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauaaguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgcccgccgguauuccggcgggcaugccuguucgag
cgucauuucaaccaucaagcccugggcuuguguuggggacccgcggcugc
ucgcgggcccugaaaagcaguggcgggcucgcuggcgggugccagccgua
aaaccc
.........................................<<<<<<<((
....>>>>.....<.<<<<.....))............>.>>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
...............<<<<<<...>>>>>>....<<<<.<<<<<<<....
>>>>>>>>>>>.........<<<<<<<<<<<<..>>>>>>.>>.>>>>..
......
Receptor-Ligand Complex Structure
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PDB8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		Y190 R193 H201 R217 V218 V219 R220 N221 K222 K223 H229 R230 F254 H256 H269 D271 L272 K274 R278 R279 F280 K281 V283 K287 M288 R291 K305 R312 R316
Binding residue
(residue number reindexed from 1)		Y7 R10 H18 R34 V35 V36 R37 N38 K39 K40 H46 R47 F71 H73 H86 D88 L89 K91 R95 R96 F97 K98 V100 K104 M105 R108 K122 R129 R133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005730 nucleolus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i9y, PDBe:8i9y, PDBj:8i9y
PDBsum8i9y
PubMed37129998
UniProtG0S1H0

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