Structure of PDB 7pub Chain CI Binding Site BS01

Receptor Information
>7pub Chain CI (length=427) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQKLLSPRTARHARLFRLAGKLADSGSPGVPKSDGERLVWVNSHVRRDKD
ISLSQEEERIRELMMPLHGNLFYFREYPMYPGEYVPAEHNTLSSLRDELR
LDLTAQSLKEAWMRVSGGVYFQSVDEYYASVDGLDAEQIGEVLAALFPEL
NCYEAQALVQRTLECISRPVSAASRQLSRTITAEAVGLDNAPGHYTNFLE
WMGRLTETRAFKTEHALFEFSRRKFNRDDVRVMFENYRLMSKATLLADSA
DSYSHFYTVLKDFARKVAGEDSRHQIGVRIDEAEVDPETGIAVGRGCADG
EKYHFTALLRENRDHNGIITVMGKPLSLVLDNKAWLMEMVLMPFDEANLD
YRDFDAHIVSEGHAMPSIANEIAAFALRMAVANALVKLIPLTRIPLKKSG
LLSVDRRRERGQFPGYLDGKKVKRRFA
Ligand information
>7pub Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaagugcug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
aaaaauauauuuuuuuuuuuu
....................<<<.......<<<<<<............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.....<<<<<.....<<....>>.......
>>>>>>>>....>>.>>>>...............................
..................................................
..............................>>>....<............
.<<<<<............................................
..................................................
.....................>>>>>..................>.....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pub Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		E385 I386 D419 R420 R421 R422 E423 R424 L431 K435 V436 K437 R438 R439 F440
Binding residue
(residue number reindexed from 1)		E371 I372 D405 R406 R407 R408 E409 R410 L417 K421 V422 K423 R424 R425 F426
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pub, PDBe:7pub, PDBj:7pub
PDBsum7pub
PubMed35042777
UniProtQ57W62

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