Structure of PDB 6rxx Chain CI Binding Site BS01 |
| >6rxx Chain CI (length=822) Species: 209285 (Thermochaetoides thermophila)
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|
ARQAARSHDIKEKRLHVPLVDRLPDEPPPRLVVIVGPPGVGKTTLLKSLV
RRYTKETMSDPVGPITVVTSKKQRLTFIECPNELEAMIDMAKVADIVLLM
IDGNYGFEMETMEFLNILANTGMPGNVFGILTHLDLFKKPSALKDAKKRL
KHRLWTELYQGAHLFYLSGVLNGRYPDREIHNLSRFLSVMKNPRPLVWRN
THPYTIIDNYRDITHPTKIEEDPLCDRTIELSGYLRGTNFAAQGQRVHIA
GVGDFTISKIEELPDPCPTPAMEKAPRRRLDEKDKKLWAPMADRSGMKIS
GDHIVITREKGFTFDKDANVERGEGEQLIVDLQGEKKLLGQTDKGVKLFA
GGEQLTQKPWRAIDLARLMYDTTLTPAQALRRWRGDYEELKTKWSNPENI
DALRRTRFQWYEMQKAMLQKQLDINKAEYAELDEHQRRQVEGYRAGKYAR
LVIEGVPAEFCKNFQPRMPILVGGLSATEDRFGFVQVRIKRHRWHKKILK
TGDPLIFSLGWRRFQTLPIYSIWDNRTRNRMLKYTPEHMHCFGTFWGPLI
APNTSFCCFQSFSASNPGFRIAATGTVLSVDESTEIVKKLKLVGTPWKIF
KNTAFIKDMFNSSLEIAKFEGAAIRTVSGIRGQIKRALSKPEGYFRATFE
DKILLSDIVILKAWYPVKPKQFYNPATNLIGWQSMRLTGEIRRAENIPTP
QNPNSTYRKIERPERHFNPLRVPKNLAAELPFKSQIVQTKPQKKETYMQK
RAVVVGREERKLRDLMQKLTTIRKEKIAKRKAKKEAQREKLKKELAEIEE
RRREKQKKEKKEFWEREGKKRK |
|
| >6rxx Chain C1 (length=1221)
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|
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgggcucugugggugggggaauucaggag
gggaaaacgauaguuaccugguugauucugcuagucauaugcuugucuca
aauaagccaugcgucuaaguauaagcaauuauacagcgaaacugcgaaug
gcucauuaaaucaguuaucguuuauuugauaguaccuuacuacauggaua
accgugguaauucuagagcuaauacaugcugaaaaucccgacuucggaag
ggauguauuuauuagauuaaaaaccaaugcccuucggggcggugauucau
aauaacuucucgaaucgcacggccuuggccggcgaugguucauucaaauu
ucugcccuaucaacuuucgacggcuggguauuggccagccguggugacaa
cggguaaggguuagggcucggagaaggagccugagaaacggcuacuacau
ccaaggaagggcaggcgcgcaaauuacccaaucccgacacggggagguag
ugacaauaaauacugauacagggcucuuucgggucuuguaauuggaauga
guacaauuuaaaucccuuaacgaggaacaauuggagggcaagucuggugc
cagcagccgcgguaauuccagcuccaauagcguauauugcucguaguuga
accugggccuagcccgccgguccgccucaccgcgugcacuggcugggcug
ggccugauuaauagggacagucgggggcgucaguauucaauugucagagg
ugaaauucuuggauuuauugaagacuaacaacugcgaaagcauucgccaa
ggauguuuucauuaaucaggaacguaaacuauuagggaucggacggcguu
uauuuuugacccguucggcaccuuacgauaggaguauggucgcaaggcug
aaaaauugacggaagggcaccaccagggguggagccugcgcgcgcgcuac
acugacagagccagcgaguacucccuuggccgagaggcccggguaaucuu
guuaaacucugucgugcuggggauagagcauugcaauuauugcucuucaa
cgaggaaucccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauagaggaaguagguc
uccguaggugaaccugcggag |
<<<<<<.<.<<<<<<....>>>>>>.>.>>>>>><<<<.<<<<....>>>
>.>>>>............................................
.................................<<.<<<<<<...<.<<.
.....<<<.<<<<<....<<....<<.........>>...>>.>>.....
.<<<.......<<<..<<..<<....<<<...............<<..<.
.<..<<.......>>..>.....>>>........<<<<<..........>
>>>><...<<<<<<..............<<<<<..>>>>>.........>
>>>>>.....>...<<<<.<<<<....>>>>>>>>....>>>...>>>>.
.>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>.....
.>>>...<<<<....>>>>.>>>.<<.<<<<........>>>>.>>.<.<
<<..>>>.>.>>>>>>.........<<<...<<<<.....>>>.>>>>..
.>...>.>....<<<<<<<<<<<<<<....>>>>>>>>>.>>>>>.....
<<..<...........>..>>.........<<<<<<.......<<<....
>>>..................>>>>>>..>>>>>>>>.<.<<...<<<.<
<...<<<<<<<<<<<<<<<<<.<<<......>>>...>>>>>>.>>>>>>
>>>>>..>>....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<.
.....>>>......>.>>>>>>.>>>.......<<....>>...>>>>..
>>.>>>.>>>...>>>...>>.>...........<<..<<<<<<<<.<<<
.......>>>>>>>>>>>..>>............................
.......<<<<<<<<<<<<..<<.<<<<<<..<<<..........>>>..
...<<<<<<<......<<.....<<<.<<<<....>>>>.>>>....>>.
......>>>>>>>...........<<<<<<..........>>>>>>....
......>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>............>>>>>..<<<<.<<......>>.>>>>...<
<<<<<<<<....>>>>>>>>> |
|
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| PDB | 6rxx Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. |
| Resolution | 7.1 Å |
Binding residue
(original residue number in PDB) | D48 K52 R53 V56 P57 L58 R325 E865 H866 M867 K929 E978 D979 P1028 S1033 P1041 E1042 R1043 H1044 N1046 P1047 L1048 R1049 V1050 K1052 A1056 W1142 E1143 G1146 K1147 |
Binding residue
(residue number reindexed from 1) | D9 K13 R14 V17 P18 L19 R278 E537 H538 M539 K601 E650 D651 P700 S705 P713 E714 R715 H716 N718 P719 L720 R721 V722 K724 A728 W814 E815 G818 K819 |
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| Enzyme Commision number |
? |
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Biological Process |
| GO:0000462 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0000479 |
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0042254 |
ribosome biogenesis |
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